MIM1 - 10mM in DMSO , CAS No.509102-00-5

CAS: 509102-00-5 Cat. No.: M656415 分子式: C₁₇H₂₁N₃O₃S 分子量: 347.43

GRADE & PURITY 10mM in DMSO

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

MIM-1 is an inhibitor of myeloid cell factor 1 ( Mcl-1 ).

In Vitro

MIM-1 selectively targets the BH3 binding groove of Mcl-1, with Bak-dependent apoptotic activity. To estimate the sensitivity of HA and T98G cells to the apoptosis inhibitor MIM-1, the colorimetric MTT assay is used to detect cell viability and to determine the IC 50 value. The IC 50 value of the HA cell line is almost 5-fold lower (16.10 µM) compared with the IC 50 of the T98G cell line (80.20 µM) after MIM-1 inhibitor treatment. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Mcl-1

Specifications

仕様と純度

10mM in DMSO

生化学的・生理学的メカニズム

MIM-1 is an inhibitor of myeloid cell factor 1 ( Mcl-1 ).

保管条件

Protected from light,Store at -80°C

入荷

Dry ice packs + Cold packs

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アクションタイプ

INHIBITOR

名前と識別子

• 分子量: 347.43