MitoMark Red I - ≥90%(HPLC) , CAS No.167095-09-2

CAS: 167095-09-2 Cat. No.: M287728 分子式: C₃₂H₃₂Cl₂N₂O 分子量: 531.52

GRADE & PURITY ≥90%(HPLC)

Synonyms

9-[4-(chloromethyl)phenyl]-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-4-ium chloride | chloromethyl-X-rosamine | 9-[4-(Chloromethyl)phenyl]-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xanthe

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

概要

MitoSceneTM Red CMXRos is a red fluorescent dye that contains chloromethyl functional groups that label mitochondria. MitoSceneTM Red CMXRos is passively transported across the cell membrane and directly accumulates on the active mitochondria after simple incubation with living cells. The accumulation of the dye depends on the membrane potential. Once the mitochondria have been stained, they can also be fixed with an aldehyde fixative as required by subsequent experiments. For immunohistochemical and in situ hybridization experiments, the cells need to be permeated first, and MitoSceneTM Red CMXRos can also stain the mitochondria of the cells. The dye is suitable for double labeling experiments, and its red fluorescence can be well distinguished from other green fluorescence probes LumiTracker Mito Red CMXRos is a cationic, red-fluorescent dye for staining active mitochondria in live cells. CMXRos is a hydrophobic compound that passively diffuses across the plasma membrane and selectively accumulates in active mitochondria based on their membrane potential. LumiTracker Mito Red CMXRos is compatible with aldehyde fixation. This dye is useful to indicate cell health as well as for mitochondria localization.

Specifications

同義語

9-[4-(chloromethyl)phenyl]-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-4-ium chloride | chloromethyl-X-rosamine | 9-[4-(Chloromethyl)phenyl]-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xanthe

仕様と純度

≥90%(HPLC)

生化学的・生理学的メカニズム

Red fluorescent mitochondrial stain. Fluorescence intensity is dependent on mitochondrial membrane potential. Excitation/emission maxima λ ~ 578/599 nm.

保管条件

Protected from light,Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

純度

≥90%(HPLC)

名前と識別子

• カノニカル・スマイル: C1CC2=CC3=C(C4=C2N(C1)CCC4)OC5=C6CCC[N+]7=C6C(=CC5=C3C8=CC=C(C=C8)CCl)CCC7.[Cl-]
• IUPAC Name: 16-[4-(chloromethyl)phenyl]-3-oxa-23-aza-9-azoniaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]octacosa-1(27),2(17),4,9(28),13,15,18-heptaene;chloride
• InChIKey: IKEOZQLIVHGQLJ-UHFFFAOYSA-M
• INCHI: 1S/C32H32ClN2O.ClH/c33-19-20-9-11-21(12-10-20)28-26-17-22-5-1-13-34-15-3-7-24(29(22)34)31(26)36-32-25-8-4-16-35-14-2-6-23(30(25)35)18-27(28)32;/h9-12,17-18H,1-8,13-16,19H2;1H/q+1;/p-1
• 異性体SMILES: C1CC2=CC3=C(C4=C2N(C1)CCC4)OC5=C6CCC[N+]7=C6C(=CC5=C3C8=CC=C(C=C8)CCl)CCC7.[Cl-]
• 分子量: 531.52
• Reaxy-Rn: 14504784
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14504784&ln=

化学的性質と物理的性質

• 溶解度: Solvent:DMSO, Max Conc. mg/mL: 0.53, Max Conc. mM: 1
• 感度: Moisture Sensitive，Light Sensitive