MitoPQ - Moligand™, ≥98% , CAS No.1821370-28-8

CAS: 1821370-28-8 Cat. No.: M275666 分子式: C₃₉H₄₆I₃N₂P 分子量: 954.48 PubChem CID: 129909777

GRADE & PURITY Moligand™, ≥98%

Synonyms

MitoParaquat

Storage

Store at 2-8°C,Protected from light,Argon charged,Desiccated

Shipped In

Wet ice

概要

MitoPQ is a mitochondria-targeted redox cycler. MitoPQ produces superoxide by redox cycling at the flavin site of complex I, selectively increasing superoxide production within mitochondria. MitoPQ can be used in antioxidant study.

Specifications

同義語

MitoParaquat

仕様と純度

Moligand™, ≥98%

生化学的・生理学的メカニズム

Selective, mitochondria-targeted redox cycler. Selectively increases superoxide production within the mitochondrial matrix in vitro and in vivo . Comprises a triphenylphosphonium lipophilic cation conjugated to the redox cycler paraquat.

保管条件

Store at 2-8°C,Protected from light,Argon charged,Desiccated

入荷

Wet ice

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

注

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

純度

≥98%

名前と識別子

• パブケム・シド: 528765637
• パブケム・シド・ウル: https://pubchem.ncbi.nlm.nih.gov/substance/528765637
• カノニカル・スマイル: C[N+]1=CC=C(C=C1)C2=CC=[N+](C=C2)CCCCCCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5.[I-].[I-].[I-]
• IUPAC Name: 10-[4-(1-methylpyridin-1-ium-4-yl)pyridin-1-ium-1-yl]decyl-triphenylphosphanium;triiodide
• InChIKey: AOZZGHKENAZYTD-UHFFFAOYSA-K
• INCHI: 1S/C39H46N2P.3HI/c1-40-30-25-35(26-31-40)36-27-32-41(33-28-36)29-17-6-4-2-3-5-7-18-34-42(37-19-11-8-12-20-37,38-21-13-9-14-22-38)39-23-15-10-16-24-39;;;/h8-16,19-28,30-33H,2-7,17-18,29,34H2,1H3;3*1H/q+3;;;/p-3
• 異性体SMILES: C[N+]1=CC=C(C=C1)C2=CC=[N+](C=C2)CCCCCCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5.[I-].[I-].[I-]
• PubChem CID: 129909777
• 分子量: 954.48

作用メカニズム

化学的性質と物理的性質

• 溶解度: Soluble in ethanol to 10 mM and in DMSO to 100 mM
• 感度: Moisture sensitive;Light sensitive
• 分子量: 954.500 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 15
• Exact Mass: 954.053 Da
• Monoisotopic Mass: 954.053 Da
• Topological Polar Surface Area: 7.800 Ų
• Heavy Atom Count: 45
• Formal Charge: 0
• Complexity: 646.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

XLogP3