MitoTEMPOL - Moligand™, ≥98% , CAS No.1101113-39-6

CAS: 1101113-39-6 Cat. No.: M275627 分子式: C₃₂H₄₂BrNO₂P 分子量: 583.57

GRADE & PURITY Moligand™, ≥98%

Synonyms

2,2,6,6-tetramethyl-4-[[5-(triphenylphosphonio)pentyl]oxy]-1-piperidinyloxy, monobromide

Storage

Protected from light,Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

概要

MitoTEMPOL is a a mitochondria-targeted nitroxide that reduces mitochondrial O2-to H2O2.

Specifications

同義語

2,2,6,6-tetramethyl-4-[[5-(triphenylphosphonio)pentyl]oxy]-1-piperidinyloxy, monobromide

仕様と純度

Moligand™, ≥98%

生化学的・生理学的メカニズム

Mitochondria-targeted antioxidant agent. SOD mimetic Tempol derivative. Protects complex I and II/III respiration. Restores MnSOD activity. Shows cardioprotective effects in vivo.

保管条件

Protected from light,Store at -20°C,Argon charged,Desiccated

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

注

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

純度

≥98%

名前と識別子

• パブケム・シド: 528765639
• カノニカル・スマイル: CC1(CC(CC(N1[O])(C)C)OCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]
• InChIKey: NCMZESLTQCMFES-UHFFFAOYSA-M
• INCHI: 1S/C32H42NO2P.BrH/c1-31(2)25-27(26-32(3,4)33(31)34)35-23-15-8-16-24-36(28-17-9-5-10-18-28,29-19-11-6-12-20-29)30-21-13-7-14-22-30;/h5-7,9-14,17-22,27H,8,15-16,23-26H2,1-4H3;1H/q+1;/p-1
• 分子量: 583.57
• Reaxy-Rn: 31789565
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=31789565&ln=

化学的性質と物理的性質

• 溶解度: Soluble in water to 100 mM；DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 10 mg/ml
• 感度: air and light sensitive