MK-0159 - ≥99% , CAS No.2641484-61-7

CAS: 2641484-61-7 Cat. No.: M648927 分子式: C₂₀H₂₄N₄O₃S 分子量: 400.49

グレード＆純度 ≥99%

Storage

Store at 2-8°C,Protected from light,Desiccated

Shipped In

Wet ice

概要

MK-0159 (compound 37) is an orally active, potent and selective CD38 inhibitor, with IC 50 values of 22, 3, and 70 nM for human, mouse and rat CD38 , respectively. MK-0159 also shows good microsomal stability for human and rodent liver microsomes. MK-0159 increases NAD + (nicotinamide adenine dinucleotide) and reduces ADPR (adenosine diphosphate ribose) in whole blood and heart

Form:Solid

IC50& Target:IC 50 : 3 nM (mouse CD38), 22 ± 5 nM (hCD38), 70 nM (rat CD38)

仕様

仕様と純度

≥99%

生化学的・生理学的メカニズム

MK-0159 (compound 37) is an orally active, potent and selective CD38 inhibitor, with IC 50 values of 22, 3, and 70 nM for human, mouse and rat CD38 , respectively. MK-0159 also shows good microsomal stability for human and rodent liver microsomes. MK-0159

保管条件

Store at 2-8°C,Protected from light,Desiccated

入荷

Wet ice

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

INHIBITOR

純度

≥99%

名前と識別子

分子量

400.49

化学的性質と物理的性質

• 溶解度: DMSO : 100 mg/mL (249.69 mM; Need ultrasonic)

よくある質問

What documentation is provided?

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