ML 218 hydrochloride - ≥99%(HPLC) , CAS No.2319922-08-0

CAS: 2319922-08-0 Cat. No.: M288331 分子式: C₁₉H₂₆Cl₂N₂O.HCl 分子量: 405.79 PubChem CID: 90488946

GRADE & PURITY ≥99%(HPLC)

Synonyms

3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]methyl]-benzamide hydrochloride

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

同義語

3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]methyl]-benzamide hydrochloride

仕様と純度

≥99%(HPLC)

生化学的・生理学的メカニズム

Selective inhibitor of T-type calcium channels (IC50values are 270 and 310 nM for Cav3.3 and Cav3.2 respectively in a patch EP assay). Decreases burst activity in STN neurons; reduces cataleptic behaviour in anin vivorat model of Parkinson's disease. Disp

保管条件

Store at 2-8°C

入荷

Wet ice

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

INHIBITOR

純度

≥99%(HPLC)

名前と識別子

カノニカル・スマイル

CC(C)(C)CCN1CC2C(C1)C2CNC(=O)C3=CC(=CC(=C3)Cl)Cl.Cl

IUPAC Name

3,5-dichloro-N-[[(1S,5R)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl]benzamide;hydrochloride

InChIKey

IDCVEUISZZKMKJ-ZXVFAPHLSA-N

INCHI

1S/C19H26Cl2N2O.ClH/c1-19(2,3)4-5-23-10-16-15(17(16)11-23)9-22-18(24)12-6-13(20)8-14(21)7-12;/h6-8,15-17H,4-5,9-11H2,1-3H3,(H,22,24);1H/t15?,16-,17+;

異性体SMILES

CC(C)(C)CCN1C[C@@H]2[C@H](C1)C2CNC(=O)C3=CC(=CC(=C3)Cl)Cl.Cl

PubChem CID

90488946

分子量

405.79

化学的性質と物理的性質

• 溶解度: Solvent:DMSO, Max Conc. mg/mL: 36.93, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 36.93, Max Conc. mM: 100

よくある質問

What is the purity of this product, and how is it determined?

This product is supplied at ≥99% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2319922-08-0, the molecular formula is C??H??Cl?N?O.HCl, and the molecular weight is 405.79 g/mol. InChIKey IDCVEUISZZKMKJ-ZXVFAPHLSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.