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MPH-220 , CAS No.2649776-79-2
AVAILABLE TO ORDER
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
MPH-220 is a selective and orally active inhibitor of skeletal muscle myosin-2. MPH-220 enables muscle relaxation. MPH-220 is anti-spastic agent that can be used in the research of spasticity and muscle stiffness.
In Vitro
MPH-220 (0-50 µM) inhibits Actin-activated ATPase activity in human muscle myosin samples. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MPH-220 (25-30 mg/kg, i.p. or oral gavage) reduces skeletal muscle force without cardiovascular effects in anesthetized rats . MPH-220 (15 mg/kg, oral administration) improves gait functions in rats with brain injury . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Anesthetized rats Dosage: 25-30 mg/kg Administration: Intraperitoneal injection (i.p.) or oral gavage Result: Reduced skeletal muscle force. Observed MPH-220 distribution in rat tissues in a time-dependent manner and a dose-dependent, few-fold accumulation in skeletal muscle.
Specifications
Biochemical and Physiological Mechanisms
MPH-220 is a selective and orally active inhibitor of skeletal muscle myosin-2 . MPH-220 enables muscle relaxation. MPH-220 is anti-spastic agent that can be used in the research of spasticity and muscle stiffness.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Names and Identifiers
| Molecular Weight | 383.46 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
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