Determine the necessary mass, volume, or concentration for preparing a solution.
MT1 - 10mM in DMSO , CAS No.2060573-82-0
注文可能
GRADE & PURITY 10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
Why this grade
10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
概要
MT1 is a bivalent chemical probe of BET bromodomains , with an IC 50 of 0.789 nM for BRD4(1).
In Vitro
MT1 (100 nM, 24 h) significantly induces apoptosis via caspase-3 and PARP in MV4;11 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisCell Line: MV4;11 cells. Concentration: 100 nM. Incubation Time: 24 h. Result: Significant apoptosis was observed by caspase-3 and PARP cleavage after treatment.
In Vivo
MT1 (44.2 and 22.1 µmol/kg, ip daily, for 14 days) significantly delayed leukemia progression in mice (Mus musculus) compared to JQ1 . MT1 exhibits terminal t 1/2 of 2.70 h in mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Leukemia xenograft models . Dosage: 44.2 and 22.1 µmol/kg. Administration: Intraperitoneally for 14 subsequent days. Result: Significantly reduced leukemic burden over the course of the study compared to either vehicle or JQ1.
Specifications
仕様と純度
10mM in DMSO
生化学的・生理学的メカニズム
MT1 is a bivalent chemical probe of BET bromodomains , with an IC 50 of 0.789 nM for BRD4(1).
保管条件
Store at -80°C
入荷
Dry ice packs + Cold packs
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
アクションタイプ
INHIBITOR
名前と識別子
| PubChem CID | 122172644 |
|---|---|
| 分子量 | 1134.20 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
証明書（CoA、COO、BSE/TSEと分析図）
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
ソリューション計算機
レビュー
顧客レビュー
よくある質問
How should this product be stored?
Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 2060573-82-0, the molecular formula is C54H66Cl2N10O9S2, and the molecular weight is 1134.20 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
Remind me later
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.