N-(2-Hydroxypropyl)methacrylamide - ≥98%(GC) , CAS No.21442-01-3

CAS: 21442-01-3 Cat. No.: N404588 分子式: C₇H₁₃NO₂ 分子量: 143.19 EC番号: 801-057-1

GRADE & PURITY ≥98%(GC)

Synonyms

AKOS006344692 | SS-4855 | H1770 | 1-(METHACRYLOYLAMINO)PROPAN-2-OL | HY-W077028 | N-(2-Hydroxypropyl)methacrylamide | OKPYIWASQZGASP-UHFFFAOYSA-N | SY238096 | ACRYLAMIDE, N-(2-HYDROXYPROPYL)-2-METHYL- | 2-Propenamide, N-(2-hydroxypropyl)-2-methyl- | A8153

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Specifications

同義語

AKOS006344692 | SS-4855 | H1770 | 1-(METHACRYLOYLAMINO)PROPAN-2-OL | HY-W077028 | N-(2-Hydroxypropyl)methacrylamide | OKPYIWASQZGASP-UHFFFAOYSA-N | SY238096 | ACRYLAMIDE, N-(2-HYDROXYPROPYL)-2-METHYL- | 2-Propenamide, N-(2-hydroxypropyl)-2-methyl- | A8153

仕様と純度

≥98%(GC)

保管条件

Store at 2-8°C,Argon charged

入荷

Wet ice

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

純度

≥98%(GC)

名前と識別子

• パブケム・シド: 508810812
• カノニカル・スマイル: CC(CNC(=O)C(=C)C)O
• IUPAC Name: N-(2-hydroxypropyl)-2-methylprop-2-enamide
• InChIKey: OKPYIWASQZGASP-UHFFFAOYSA-N
• INCHI: 1S/C7H13NO2/c1-5(2)7(10)8-4-6(3)9/h6,9H,1,4H2,2-3H3,(H,8,10)
• 異性体SMILES: CC(CNC(=O)C(=C)C)O
• 分子量: 143.19
• Reaxy-Rn: 2074155
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2074155&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • 分類 Carboxylic acids and derivatives
      • Subclass Carboxylic acid derivatives
        • Level5 Carboxylic acid amides
          • Level6 Secondary carboxylic acid amides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• 分類: Carboxylic acids and derivatives
• Subclass: Carboxylic acid derivatives
• Intermediate Tree Nodes: Carboxylic acid amides
• Direct Parent: Secondary carboxylic acid amides
• Alternative Parents: Secondary alcohols Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Secondary carboxylic acid amide - Secondary alcohol - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Alcohol - Aliphatic acyclic compound
• 説明: This compound belongs to the class of organic compounds known as secondary carboxylic acid amides. These are compounds containing a secondary carboxylic acid amide functional group, with the general structure RC(=O)N(R')H (R,R'=alkyl, aryl).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

化学的性質と物理的性質

• 感度: Air & Heat & Moisture Sensitive
• 融点（°C）: 70 °C
• 分子量: 143.180 g/mol
• XLogP3: 0.300
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 143.095 Da
• Monoisotopic Mass: 143.095 Da
• Topological Polar Surface Area: 49.300 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 143.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

参考文献

1. Qingqing Yang, Yang Yang, Lian Li, Wei Sun, Xi Zhu, Yuan Huang.  (2015)  Polymeric Nanomedicine for Tumor-Targeted Combination Therapy to Elicit Synergistic Genotoxicity against Prostate Cancer.  ACS Applied Materials & Interfaces,      [PMID:25775367] [10.1021/am509204u]

2. Changyong Guo, Shipeng He, Huaxing Shen, Wei Cong, Jinqiu Li, Yajing Ji, Wenjing Huang, Fei Gao, Honggang Hu.  (2025)  Polymer-assisted PD-L1 degradation and targeted photodynamic therapy synergize to suppress immunodeficient tumors.  Acta Pharmaceutica Sinica B,      [PMID:40698133] [10.1016/j.apsb.2025.05.022]