NDSB-221 - ≥97% , CAS No.160788-56-7

CAS: 160788-56-7 Cat. No.: N276111 分子式: C₉H₁₉NO₃S 分子量: 221.32 EC番号: 687-439-7

グレード＆純度 ≥97%

Synonyms

NDSB 221 | 3-(1-methylpiperidinio)-1-propanesulfonate | J-009754 | SCHEMBL2396073 | non-detergent sulfobetaine 221 | DTXSID001213424 | 3-(1-Methylpiperidin-1-ium-1-yl)propane-1-sulfonate | HY-135463 | CHEBI:63318 | LCZC1460 | non detergent sulfobetaine 22

Storage

室温、アルゴンチャージ

Shipped In

ノーマル

概要

製品説明
NDSB 221は非洗浄性スルホベタインで、アンフォールディングの可逆性を改善することが見出されています。
製品用途

NDSB 221は、Thermococcus onnurineus由来のホスホセリンホスファターゼの新規リガンド結合部位を同定する研究に使用されました。また、酸性線維芽細胞増殖因子（aFGF）に対する作用を調べる研究にも使用されています。
非変性スルホベタインは、非変性プロテインの精製に使用される化合物である。膜、核、細胞骨格に関連するタンパク質の抽出収量を増加させる。広いpH範囲で双性イオン性であり、透析で容易に除去でき、近紫外領域で顕著な吸収はない。具体的な用途としては、ミクロソームタンパク質の抽出、核タンパク質の回収、IEFにおける沈殿の減少、膜結合プロテアーゼの精製などが挙げられる。一般的な使用濃度は0.5～2.0M。

仕様

同義語

NDSB 221 | 3-(1-methylpiperidinio)-1-propanesulfonate | J-009754 | SCHEMBL2396073 | non-detergent sulfobetaine 221 | DTXSID001213424 | 3-(1-Methylpiperidin-1-ium-1-yl)propane-1-sulfonate | HY-135463 | CHEBI:63318 | LCZC1460 | non detergent sulfobetaine 22

仕様と純度

≥97%

生化学的・生理学的メカニズム

Zwitterionic non-detergent sulfobetaine. Used to extract, solubilise and crystallise proteins. Prevents protein aggregation and promotes renaturation of denatured proteins.

保管条件

室温、アルゴンチャージ

入荷

ノーマル

注

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

純度

≥97%

名前と識別子

パブケム・シド

488196547

パブケム・シド・ウル

https://pubchem.ncbi.nlm.nih.gov/substance/488196547

カノニカル・スマイル

C[N+]1(CCCCC1)CCCS(=O)(=O)[O-]

IUPAC Name

3-(1-methylpiperidin-1-ium-1-yl)propane-1-sulfonate

InChIKey

DQNQWAVIDNVATL-UHFFFAOYSA-N

INCHI

1S/C9H19NO3S/c1-10(6-3-2-4-7-10)8-5-9-14(11,12)13/h2-9H2,1H3

異性体SMILES

C[N+]1(CCCCC1)CCCS(=O)(=O)[O-]

分子量

221.32

Reaxy-Rn

30123612

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30123612&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 分類 Piperidines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 分類: Piperidines
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Piperidines
• Alternative Parents: Tetraalkylammonium salts Sulfonyls Organosulfonic acids Alkanesulfonic acids Azacyclic compounds Organopnictogen compounds Organic salts Organic oxides Hydrocarbon derivatives Amines
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Piperidine - Quaternary ammonium salt - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Organosulfonic acid - Sulfonyl - Alkanesulfonic acid - Tetraalkylammonium salt - Azacycle - Organic nitrogen compound - Organosulfur compound - Organonitrogen compound - Organic salt - Hydrocarbon derivative - Amine - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aliphatic heteromonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as piperidines. These are compounds containing a piperidine ring, which is a saturated aliphatic six-member ring with one nitrogen atom and five carbon atoms.
• External Descriptors: ammonium betaine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

化学的性質と物理的性質

• 溶解度: Soluble in water to 100 mM
• 感度: Moisture sensitive
• 分子量: 221.320 g/mol
• XLogP3: 0.300
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 221.109 Da
• Monoisotopic Mass: 221.109 Da
• Topological Polar Surface Area: 65.600 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 249.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1