NS 383 - Moligand™ , Channel blocker of ASIC1;Channel blocker of ASIC3, CAS No.309711-59-9, Channel blocker of ASIC1;Channel blocker of ASIC3

CAS: 309711-59-9 Cat. No.: N288698 分子式: C₁₉H₁₉N₃O₂ 分子量: 321.37 PubChem CID: 135418391

GRADE & PURITY Moligand™

Synonyms

8-Ethyl-6,7,8,9-tetrahydro-5-phenyl-1H-pyrrolo[3,2-h]isoquinoline-2,3-dione-3-oxime

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

同義語

8-Ethyl-6,7,8,9-tetrahydro-5-phenyl-1H-pyrrolo[3,2-h]isoquinoline-2,3-dione-3-oxime

仕様と純度

Moligand™

生化学的・生理学的メカニズム

ASIC blocker (IC50values are 0.44, 2.1 μM and no effect at rat ASIC1a, ASIC3 and ASIC2a, respectively: IC50value = 0.12 μM at human ASIC1a with no effect at ASIC2a or ASIC3). Inhibition was also observed at heteromeric ASIC channels (IC50values are 0.79,

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

CHANNEL BLOCKER

作用メカニズム

Channel blocker of ASIC1;Channel blocker of ASIC3

名前と識別子

• カノニカル・スマイル: CCN1CCC2=C(C=C3C(=C2C1)NC(=C3N=O)O)C4=CC=CC=C4
• IUPAC Name: 8-ethyl-3-nitroso-5-phenyl-1,6,7,9-tetrahydropyrrolo[3,2-h]isoquinolin-2-ol
• InChIKey: OZVZKENYKWSYBC-UHFFFAOYSA-N
• INCHI: 1S/C19H19N3O2/c1-2-22-9-8-13-14(12-6-4-3-5-7-12)10-15-17(16(13)11-22)20-19(23)18(15)21-24/h3-7,10,20,23H,2,8-9,11H2,1H3
• PubChem CID: 135418391
• 分子量: 321.37

関連ターゲット（人間）

ASIC3 Tchem Acid-sensing ion channel 3 (0 Activities)

Discover Target: ASIC3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ASIC1 Tchem Acid-sensing ion channel 1 (0 Activities)

Discover Target: ASIC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

化学的性質と物理的性質

• 溶解度: Solvent:DMSO, Max Conc. mg/mL: 1.61, Max Conc. mM: 5

よくある質問

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 309711-59-9, the molecular formula is C??H??N?O?, and the molecular weight is 321.37 g/mol. InChIKey OZVZKENYKWSYBC-UHFFFAOYSA-N.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.