NXPZ-2 - ≥98% , CAS No.2254492-08-3

CAS: 2254492-08-3 Cat. No.: N1447741 分子式: C₂₇H₂₇N₅O₇S₂ 分子量: 597.66

GRADE & PURITY ≥98%

Storage

Store at 2-8°C

Shipped In

Wet ice

概要

NXPZ-2 is an orally active Keap1-Nrf2 protein–protein interaction (PPI) inhibitor with a K i value of 95 nM, EC 50 value of 120 and 170 nM. NXPZ-2 can dose-dependently ameliorate Aβ [1-42] -Induced cognitive dysfunction , improve brain tissue pathological changes in Alzheimer’s disease (AD) mouse by increasing neuron quantity and function. NXPZ-2 can inhibit oxidative stress by increasing Nrf2 expression levels and promoting its cytoplasm to nuclear translocation, which is helpful for Keap1-Nrf2 PPI inhibitors and AD associated disease research.

Specifications

仕様と純度

≥98%

保管条件

Store at 2-8°C

入荷

Wet ice

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

INHIBITOR

純度

≥98%

名前と識別子

• 分子量: 597.66

よくある質問

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2254492-08-3, the molecular formula is C27H27N5O7S2, and the molecular weight is 597.66 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.