OARV-771 - ≥98% , CAS No.2683008-37-7

CAS: 2683008-37-7 Cat. No.: O651646 分子式: C₄₉H₅₉ClN₈O₈S₂ 分子量: 987.62

グレード＆純度 ≥98%

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Application

PROTAC

概要

OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. OARV-771 shows DC 50 s of 6, 1, and 4 nM for Brd4 , Brd2 and Brd3 , respectively

In Vitro

OARV-771 shows antiproliferative effect with an EC 50 value of 4 nM in MV4;11. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:BRD4 6 nM (DC 50 ) BRD2 1 nM (DC 50 ) BRD3 4 nM (DC 50 ) VHL

仕様

仕様と純度

≥98%

生化学的・生理学的メカニズム

OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. OARV-771 shows DC 50 s of 6, 1, and 4 nM for Brd4 , Brd2 and Brd3 , respectively.

保管条件

Store at -20°C,Desiccated

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

INHIBITOR

純度

≥98%

名前と識別子

分子量

987.62

化学的性質と物理的性質

• 溶解度: DMSO : 100 mg/mL (101.25 mM; Need ultrasonic)