OARV-771 - 10mM in DMSO , CAS No.2683008-37-7

CAS: 2683008-37-7 Cat. No.: O656762 分子式: C₄₉H₅₉ClN₈O₈S₂ 分子量: 987.62

グレード＆純度 10mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. OARV-771 shows DC 50 s of 6, 1, and 4 nM for Brd4 , Brd2 and Brd3 , respectively

In Vitro

OARV-771 shows antiproliferative effect with an EC 50 value of 4 nM in MV4;11. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:BRD4 6 nM (DC 50 ) BRD2 1 nM (DC 50 ) BRD3 4 nM (DC 50 ) VHL

仕様

仕様と純度

10mM in DMSO

生化学的・生理学的メカニズム

OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. OARV-771 shows DC 50 s of 6, 1, and 4 nM for Brd4 , Brd2 and Brd3 , respectively.

保管条件

Desiccated,Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

INHIBITOR

名前と識別子

分子量

987.62

よくある質問

How should this product be stored?

Store at ?80 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2683008-37-7, the molecular formula is C49H59ClN8O8S2, and the molecular weight is 987.62 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.