P110 TFA - 10mM in DMSO , CAS No.P110(DMSO)

CAS: P110(DMSO) Cat. No.: P580476 分子式: C₁₀₀H₁₇₉N₄₅O₂₅(free) 分子量: 2411.78(free)

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Information

P110 P110 is a dynamin-related protein 1 (Drp1) -specific inhibitor that binds directly to Drp1.

Targets

Drp1

In vitro

P110 is a Drp1-specific inhibitor that binds directly to Drp1. In some cases, this binding inhibits translocation to the mitochondria or prevents mitochondrial docking.

In vivo

P110 treatment inhibits the interaction of fission proteins Fis1/Drp1, decreases mitochondrial fission, and improves bioenergetics in three different rat models of IR, including primary cardiomyocytes, ex vivo heart model, and an in vivo myocardial infarction model.

Cell Research(from reference)

Cell lines：Primary cardiac myocytes 

Concentrations：1 μmol/L 

Incubation Time：2h + 2 to 60 min 

Specifications

仕様と純度

10mM in DMSO

生化学的・生理学的メカニズム

P110 is a dynamin-related protein 1 (Drp1)-specific inhibitor that binds directly to Drp1.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

名前と識別子

• 分子量: 2411.78(free)

化学的性質と物理的性質

• 溶解度: Solubility (25°C) In vitro DMSO: 100 mg/mL (41.46 mM); Water: 100 mg/mL (41.46 mM); Ethanol: Insoluble