ペオノール - ≥99% , CAS No.552-41-0

CAS: 552-41-0 Cat. No.: H111081 分子式: C9H10O3 分子量: 166.17 Beilstein Registry Number: 8267 EC番号: 209-012-2
注文可能
GRADE & PURITY ≥99%
Synonyms
1-(2-ヒドロキシ-4-メトキシフェニル)エタン-1-オン|AC-7982|AM20040702|HMS3656E07|PAEONOL [WHO-DD]|SW219250-1|Z57101020|Q7124105|RESACETOPHENONE 4-O-METHYLエーテル|NCGC00095977-03|CCG-39471|FT-0618875|PAEONOL|4-08-00-01793 (Beilstein Handboo)
Storage
Room temperature
Shipped In
ノーマル
★
Size
USA
ドイツ (EU)*
Price
Qty
1g
H111081-1g
9 在庫あり
—

$9.90

$14.90
保存 $5.00 (33.56%)
5g
H111081-5g
5 在庫あり
—

$11.90

$17.90
保存 $6.00 (33.52%)
10g
H111081-10g
受注生産 · 8~12週間

$14.90

$22.90
保存 $8.00 (34.93%)
25g
H111081-25g
4 在庫あり
—

$24.90

$37.90
保存 $13.00 (34.30%)
100g
H111081-100g
5 在庫あり
—

$61.90

$92.90
保存 $31.00 (33.37%)
500g
H111081-500g
1 在庫あり
—

$159.90

$239.90
保存 $80.00 (33.35%)
Enter a quantity for the sizes you want to add.
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships ノーマル Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 18 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

概要

PaeonolはPaeonia suffruticosa Andr.から単離された有効成分である。その薬理作用には、抗凝集作用、抗炎症作用、抗虚血再灌流障害作用、抗脂質過酸化作用などがある。
抗炎症・抗脂質過酸化作用

Specifications

同義語
1-(2-ヒドロキシ-4-メトキシフェニル)エタン-1-オン|AC-7982|AM20040702|HMS3656E07|PAEONOL [WHO-DD]|SW219250-1|Z57101020|Q7124105|RESACETOPHENONE 4-O-METHYLエーテル|NCGC00095977-03|CCG-39471|FT-0618875|PAEONOL|4-08-00-01793 (Beilstein Handboo)
仕様と純度
≥99%
生化学的・生理学的メカニズム
強力な抗炎症・抗酸化剤。内因性の抗酸化活性を高める。BaxとCaspase-3の発現を減少させる。生体内で抗虚血作用、腎保護作用、心保護作用を示す。経口活性。
保管条件
Room temperature
入荷
ノーマル
アクションタイプ
INHIBITOR
注
可能な限り、溶液はその日のうちに調製し、使用すること。ただし、事前にストック溶液を調製する必要がある場合は、密栓したバイアルに分注した溶液を-20℃で保存することをお勧めします。通常、これらは1ヶ月間使用可能です。使用前、バイアルを開封する前に、製品を少なくとも1時間室温に平衡化させることをお勧めします。溶解性、使用方法、取り扱いについて、さらに詳しいアドバイスが必要ですか?詳しくは、よくある質問(FAQ)のページをご覧ください。
純度
≥99%
名前と識別子
パブケム・シド488181255
パブケム・シド・ウルhttps://pubchem.ncbi.nlm.nih.gov/substance/488181255
カノニカル・スマイルCC(=O)C1=C(C=C(C=C1)OC)O
IUPAC Name1-(2-hydroxy-4-methoxyphenyl)ethanone
InChIKeyUILPJVPSNHJFIK-UHFFFAOYSA-N
INCHI1S/C9H10O3/c1-6(10)8-4-3-7(12-2)5-9(8)11/h3-5,11H,1-2H3
異性体SMILES CC(=O)C1=C(C=C(C=C1)OC)O
WGKドイツ 3
RTECS RT1215000
分子量 166.17
Beilstein 8267
Reaxy-Rn 1282794
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1282794&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic oxygen compounds
分類Organooxygen compounds
SubclassCarbonyl compounds
Intermediate Tree Nodes Ketones - Aryl ketones - Phenylketones
Direct ParentAlkyl-phenylketones
Alternative Parents Methoxyphenols  Acetophenones  Phenoxy compounds  Methoxybenzenes  Benzoyl derivatives  Aryl alkyl ketones  Anisoles  Alkyl aryl ethers  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Vinylogous acids  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Alkyl-phenylketone - Methoxyphenol - Acetophenone - Phenoxy compound - Anisole - Benzoyl - Phenol ether - Aryl alkyl ketone - Methoxybenzene - Phenol - 1-hydroxy-4-unsubstituted benzenoid - Alkyl aryl ether - 1-hydroxy-2-unsubstituted benzenoid - Benzenoid - Monocyclic benzene moiety - Vinylogous acid - Ether - Hydrocarbon derivative - Organic oxide - Aromatic homomonocyclic compound
説明This compound belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group.
External Descriptors phenols - methoxybenzene
3 D構造
インタラクティブ化学構造モデル





関連ターゲット(人間)
TYR Tclin Tyrosinase (717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CACNA1C Tclin Voltage-gated L-type calcium channel alpha-1C subunit (766 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AKR1B1 Tclin Aldose reductase (1404 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
M14 (47487 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
関連ターゲット(非人間)
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
作用メカニズム
証明書(CoA、COO、BSE/TSEと分析図)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

25 results found

Lot NumberCertificate Type日付商品
D2314557Certificate of AnalysisSep 21, 2026 H111081
E2112323Certificate of AnalysisJul 30, 2026 H111081
F2512546Certificate of AnalysisJun 16, 2025 H111081
E1802020Certificate of AnalysisJun 12, 2025 H111081
E1802021Certificate of AnalysisJun 12, 2025 H111081
L2107549Certificate of AnalysisJun 09, 2025 H111081
L2107548Certificate of AnalysisJun 09, 2025 H111081
D2527243Certificate of AnalysisMay 09, 2025 H111081
D2527240Certificate of AnalysisMay 09, 2025 H111081
D2527241Certificate of AnalysisMay 09, 2025 H111081
D2527242Certificate of AnalysisMay 09, 2025 H111081
D2527250Certificate of AnalysisMay 09, 2025 H111081
D2514040Certificate of AnalysisApr 29, 2025 H111081
G2319512Certificate of AnalysisApr 09, 2025 H111081
G2319494Certificate of AnalysisApr 09, 2025 H111081
G2319480Certificate of AnalysisApr 09, 2025 H111081
C1610281Certificate of AnalysisMar 04, 2025 H111081
E2112325Certificate of AnalysisNov 07, 2024 H111081
G2024096Certificate of AnalysisFeb 21, 2024 H111081
E2223161Certificate of AnalysisFeb 21, 2024 H111081
E2223164Certificate of AnalysisFeb 21, 2024 H111081
E2223165Certificate of AnalysisFeb 21, 2024 H111081
E2223168Certificate of AnalysisFeb 21, 2024 H111081
L2107523Certificate of AnalysisSep 20, 2023 H111081
L2107547Certificate of AnalysisSep 20, 2023 H111081

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化学的性質と物理的性質
溶解度Soluble in water (<1 mg/ml at 25 °C), methanol, DMSO (33 mg/ml at 25 °C), and ethanol (33 mg/ml at 25 °C).
屈折率1.54
引火点(°F)235.4 °F
引火点(°C)113 °C
沸点(°C)154°C/20mmHg
融点(°C)47-50°C
分子量166.170 g/mol
XLogP32.000
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass166.063 Da
Monoisotopic Mass166.063 Da
Topological Polar Surface Area46.500 Ų
Heavy Atom Count12
Formal Charge0
Complexity167.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
参考文献
1. Chen Chen, Xiao Yang, Xian-hui Shao, Yue Zhou, Xiao-bin Zhang, Yun-ping Lu, Meng-zhen Xing, Qing-chang Xia, Yuan-xiang Liu, Yu-ning Ma, Ting-ting Zheng, Lin-lin Zhang, Yu-xia Ma, Ji-guo Yang.  (2023)  Thermal-grinding supramolecular network loaded with paeonol for treatment of skin eczema.  CHEMICAL ENGINEERING SCIENCE,      [PMID:] [10.1016/j.ces.2023.119096]
2. Xin Li, Huimei Shi, Di Zhang, Bei Jing, Zhenni Chen, Yachun Zheng, Shiquan Chang, Li Gao, Guoping Zhao.  (2023)  Paeonol alleviates neuropathic pain by modulating microglial M1 and M2 polarization via the RhoA/p38MAPK signaling pathway.  CNS Neuroscience & Therapeutics,      [PMID:37032648] [10.1111/cns.14211]
3. Shuai Liu, Keming Zheng, Yilin Jiang, Susu Gai, Bohan Li, Dehai Li, Shuang Yang, Zhihua Lv.  (2023)  Biotransformation of Penindolone, an Influenza A Virus Inhibitor.  MOLECULES,  28  (3): (1479).  [PMID:36771146] [10.3390/molecules28031479]
4. Songjun Liu, Xinran Cao, Tao Zhang, Chenyang Zhang, Jiao Qu, Yang Sun, Wen Lv, Fan Qu.  (2022)  Paeonol ameliorates endometrial hyperplasia in mice via inhibiting PI3K/AKT pathway-related ferroptosis.  PHYTOMEDICINE,      [PMID:36610113] [10.1016/j.phymed.2022.154593]
5. Siying Wang, Lanlan Xie, Qilei Yang, Yuting Geng, Hedi Kang, Xiuhua Zhao.  (2022)  Extraction and purification of paeonol from Moutan Cortex by a combined method of steam distillation and antisolvent recrystallization to reduce energy consumption and carbon dioxide emissions.  CANADIAN JOURNAL OF CHEMICAL ENGINEERING,  101  (7): (3771-3785).  [PMID:] [10.1002/cjce.24732]
6. Yuling Wang, Zeyan Tang, Xueping Guo, Yuqi Zhao, Shujing Ren, Zhenhai Zhang, Huixia Lv.  (2022)  Hyaluronic acid-cyclodextrin encapsulating paeonol for treatment of atopic dermatitis.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,      [PMID:35714817] [10.1016/j.ijpharm.2022.121916]
7. Zhiping Che, Xiaolong Guo, Yuanhao Li, Song Zhang, Lina Zhu, Jiaxuan He, Di Sun, Yihao Guo, Yibo Liu, Ruxue Wei, Xiaobo Huang, Shengming Liu, Genqiang Chen, Yuee Tian.  (2022)  Synthesis of paeonol ester derivatives and their insecticidal, nematicidal, and anti-oomycete activities.  PEST MANAGEMENT SCIENCE,  78  (8): (3442-3455).  [PMID:35567371] [10.1002/ps.6985]
8. Yipeng Gu, Kai Chen, Bingwen Xi, Jun Xie, Xuwen Bing.  (2022)  Paeonol increases the antioxidant and anti-inflammatory capacity of gibel carp (Carassius auratus gibelio) challenged with Aeromonas hydrophila.  FISH & SHELLFISH IMMUNOLOGY,      [PMID:35314333] [10.1016/j.fsi.2022.03.005]
9. Yue-E Tian, Di Sun, Xiao-Xiao Han, Jin-Ming Yang, Song Zhang, Nan-Nan Feng, Li-Na Zhu, Zhong-Yuan Xu, Zhi-Ping Che, Sheng-Ming Liu, Xiao-Min Lin, Jia Jiang, Gen-Qiang Chen.  (2021)  Synthesis, anti-oomycete activity, and SAR studies of paeonol derivatives.  JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,      [PMID:32009450] [10.1080/10286020.2020.1718116]
10. Chunqing Niu, Xiang Li, Yiyu Wang, Xinyu Liu, Jian Shi, Xinyu Wang.  (2019)  Design and performance of a poly(vinyl alcohol)/silk fibroin enzymatically crosslinked semi-interpenetrating hydrogel for a potential hydrophobic drug delivery.  RSC Advances,  9  (70): (41074-41082).  [PMID:35540084] [10.1039/C9RA09344C]
11. Jingjing Yao, Yangxin Zhang, Qiming Hu, Decheng Zeng, Fang Hua, Wei Meng, Weiyun Wang, Guan-Hu Bao.  (2017)  Optimization of paeonol-loaded poly(butyl-2-cyanoacrylate) nanocapsules by central composite design with response surface methodology together with the antibacterial properties.  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES,      [PMID:28189814] [10.1016/j.ejps.2017.01.028]
12. Jingjing Yao, Decheng Zeng, Yangxin Zhang, Dongdong Sun, Endong Yang, Haiping Liu, Feng Guo, Weiyun Wang.  (2016)  Effect of solvents on forming poly(butyl-2-cyanoacrylate) encapsulated paeonol nanocapsules.  JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION,      [PMID:27846779] [10.1080/09205063.2016.1262161]
13. Xie Xiaoyu, Pan Xiaoyan, Han Shengli, Wang Sicen.  (2015)  Development and characterization of magnetic molecularly imprinted polymers for the selective enrichment of endocrine disrupting chemicals in water and milk samples.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  407  (6): (1735-1744).  [PMID:25577356] [10.1007/s00216-014-8425-0]
14. Ping Mao, Xiao Wei, Mo Liqian, Xiao Xiaoyan, Song Shaolian, Tang Waijiao, Yang Xixiao.  (2014)  Paeonol Attenuates Advanced Oxidation Protein Product-Induced Oxidative Stress Injury in THP-1 Macrophages.  PHARMACOLOGY,      [PMID:25170865] [10.1159/000363577]
15. Xin Li, Zifeng Zhuang, Yuting Hao, Shaozi Lin, Junyan Gu, Shiquan Chang, Lin Lan, Guoping Zhao, Di Zhang.  (2025)  Paeonol Relieves Chronic Neuropathic Pain by Reducing Communication Between Schwann Cells and Macrophages in the Dorsal Root Ganglia After Injury.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  26  (9): (3964).  [PMID:40362205] [10.3390/ijms26093964]
16. Miao Li, Na Gao, Lei Xu, Peng Ge, Nan Jiang, Yuhong Shang.  (2025)  Integrative RNA-seq and LASSO-COX analysis reveal Paeonol’s key target gene in proliferation suppression and apoptosis-induced in cervical cancer.  Frontiers in Pharmacology,      [PMID:41126956] [10.3389/fphar.2025.1646473]
17. Xu Chen, Jianxing Liu, Yongrui Liang, Zihan Gong.  (2026)  Paeonol inhibits the progression of endometrial cancer by affecting TRIM26-mediated LDHA ubiquitination modification.  TISSUE & CELL,      [PMID:41691946] [10.1016/j.tice.2026.103359]
18. Liu-Jie Qi, Zhao-Qi Zhang, Zhong-Na Zhang, Jing-An Li, Shao-Kang Guan.  (2026)  Theoretical calculation-experimental collaborative design of integrated coating for degradation regulation and diagnosis-treatment of magnesium alloy for cerebrovascular stents.  Journal of Advanced Research,      [PMID:41713732] [10.1016/j.jare.2026.02.028]
19. Yanpin Ma, Yihao Guo, Jiaxuan He, Yuee Tian, Lin Zhou, Zhiping Che.  (2026)  Non-food bioactive products: Design, synthesis, anti-oomycete, and anti-fungal activities of novel paeonol oxime ether derivatives containing isoxazoline/isoxazole fragments.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2026.124053]
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よくある質問

What is the purity of this product?
This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at room temperature.
How is this product shipped?
This product ships under standard ambient conditions. No temperature-controlled packaging is required.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 552-41-0, the molecular formula is C9H10O3, and the molecular weight is 166.17 g/mol. InChIKey UILPJVPSNHJFIK-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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