Pemetrexed hydrate - ≥98%, contains

CAS: 137281-23-3(anhy) Cat. No.: P1493015 分子式: C₂₀H₂₁N₅O₆·xH₂O 分子量: 427.41（anhy） EC番号: 680-625-9

GRADE & PURITY ≥98%, contains <4%EtOH

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

概要

Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.

Specifications

仕様と純度

≥98%, contains <4%EtOH

生化学的・生理学的メカニズム

High affinity dihydrofolate reductase inhibitor (Ki= 7 nM). Also inhibits thymidylate synthase, AICART and glycinamide ribonucleotide formyltransferase (Kivalues are 109 nM, and 3.5 μM and 9.3 μM, respectively). Indirectly activates AMPK. Inhibits prolife

保管条件

Store at 2-8°C,Protected from light

入荷

Wet ice

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

純度

≥98%

名前と識別子

• 分子量: 427.41（anhy）

化学的性質と物理的性質

• 溶解度: Solvent:DMSO, Max Conc. mg/mL: 42.74, Max Conc. mM: 100
• 感度: Heat Sensitive;light sensitive