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224,000+ 研究の概要 · Triple ISO certified · COA & SDS すべての製品に適用 · 在庫品は当日出荷 PF 915275 - ≥98%(HPLC) , CAS No.857290-04-1
Synonyms
PF-915275; PF915275 | PF-915275 | SCHEMBL4384483 | BDBM29864 | N-(6-Amino-2-pyridinyl)-4'-cyano-[1,1'-biphenyl]-4-sulfonamide | BCP28049 | 4'-cyano-biphenyl-4-sulfonic acid (6-amino-pyridin-2-yl)-amide | EC-000.2428 | N-(Pyridin-2-yl) arylsulfonamide, 26
Shipped In
Ice chest + Ice pads
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Why this grade ≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications 同義語
PF-915275; PF915275 | PF-915275 | SCHEMBL4384483 | BDBM29864 | N-(6-Amino-2-pyridinyl)-4'-cyano-[1,1'-biphenyl]-4-sulfonamide | BCP28049 | 4'-cyano-biphenyl-4-sulfonic acid (6-amino-pyridin-2-yl)-amide | EC-000.2428 | N-(Pyridin-2-yl) arylsulfonamide, 26
生化学的・生理学的メカニズム
Potent and selective 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor (Ki= 2.3 nM) that displays little activity at 11βHSD2 (1.5% inhibition at 10μM). Inhibits the conversion of prednisone to prednisolone in human hepatocytesin vitro(EC50= 15 n
入荷
Ice chest + Ice pads
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
名前と識別子 カノニカル・スマイル
C1=CC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N
IUPAC Name
N-(6-aminopyridin-2-yl)-4-(4-cyanophenyl)benzenesulfonamide
InChIKey
ZESFDAKNYJQYKO-UHFFFAOYSA-N
INCHI
1S/C18H14N4O2S/c19-12-13-4-6-14(7-5-13)15-8-10-16(11-9-15)25(23,24)22-18-3-1-2-17(20)21-18/h1-11H,(H3,20,21,22)
異性体SMILES
C1=CC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids 分類 Benzene and substituted derivatives Subclass Biphenyls and derivatives Intermediate Tree Nodes Not available Direct Parent Biphenylcarbonitriles Alternative Parents Benzenesulfonamides Benzenesulfonyl compounds Benzonitriles Aminopyridines and derivatives Organosulfonamides Imidolactams Heteroaromatic compounds Aminosulfonyl compounds Nitriles Azacyclic compounds Primary amines Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Biphenylcarbonitrile - Benzenesulfonamide - Benzenesulfonyl group - Benzonitrile - Aminopyridine - Pyridine - Imidolactam - Organosulfonic acid amide - Heteroaromatic compound - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Aminosulfonyl compound - Sulfonyl - Carbonitrile - Nitrile - Azacycle - Organoheterocyclic compound - Organosulfur compound - Organonitrogen compound - Organic nitrogen compound - Amine - Organic oxide - Cyanide - Primary amine - Hydrocarbon derivative - Organic oxygen compound - Aromatic heteromonocyclic compound 説明 This compound belongs to the class of organic compounds known as biphenylcarbonitriles. These are organic compounds containing an acetonitrile with one hydrogen replaced by a biphenyl group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3 D構造 関連ターゲット(人間) 関連ターゲット(非人間) 作用メカニズム 証明書(CoA、COO、BSE/TSEと分析図) 化学的性質と物理的性質 溶解度 Solvent:DMSO, Max Conc. mg/mL: 35.04, Max Conc. mM: 100 分子量 350.400 g/mol XLogP3 2.700 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 4 Exact Mass 350.084 Da Monoisotopic Mass 350.084 Da Topological Polar Surface Area 117.000 Ų Heavy Atom Count 25 Formal Charge 0 Complexity 578.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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