PF-9366 - 10mM in DMSO , CAS No.72882-78-1

CAS: 72882-78-1 Cat. No.: P425692 分子式: C₂OH₁₉ClN₄ 分子量: 350.84 PubChem CID: 12612431

GRADE & PURITY 10mM in DMSO

Synonyms

[1,​2,​4]​Triazolo[4,​3-​a]​quinoline-​1-​ethanamine,7-​chloro-​N,​N-​dimethyl-​5-​phenyl-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Information

PF-9366 PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor with IC50 of 420 nM and Kd of 170 nM.

Targets

hMat2A (Cell-free assay); hMat2A (Cell-free assay) 170 nM(Kd); 420 nM

Specifications

同義語

[1,​2,​4]​Triazolo[4,​3-​a]​quinoline-​1-​ethanamine,7-​chloro-​N,​N-​dimethyl-​5-​phenyl-

仕様と純度

10mM in DMSO

生化学的・生理学的メカニズム

PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor with IC50 of 420 nM and Kd of 170 nM.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

製品の性質

• ALogP: 4.355
• hba_count: 2
• 回転可能な結合: 4

名前と識別子

• 異性体SMILES: CN(C)CCC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=C2)C4=CC=CC=C4
• PubChem CID: 12612431
• 分子量: 350.84

関連ターゲット（人間）

MAT2A Tchem S-adenosylmethionine synthase isoform type-2 (713 Activities)

Discover Target: MAT2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

関連ターゲット（非人間）

Mus musculus (284745 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用メカニズム

化学的性質と物理的性質

• DMSO（mg / mL） 最大溶解度: 15
• DMSO（mM） 最大溶解度: 42.7545319803899
• 水（mg / mL） 最大溶解度: ˂1

よくある質問

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 72882-78-1, the molecular formula is C20H19ClN4, and the molecular weight is 350.84 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.