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Pirfenidone - Moligand™, ≥98%(GC) , CAS No.53179-13-8

CAS: 53179-13-8 Cat. No.: P129335 分子式: C12H11NO 分子量: 185.22 Beilstein Registry Number: 21(5)7,197 EC番号: 621-260-7
19 Citations COA
Pirfenidone - Moligand™, ≥98%(GC) CAS No(53179-13-8) by Aladdin Scientific
注文可能
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(GC)
Synonyms
MFCD00866047 | Pirfenidona [INN-Spanish] | PIRFENIDONE [INN] | Pirfenidone(AMR69) | 5-Methyl-1-phenyl-2(1H)-pyridone | ESBRIET COMPONENT PIRFENIDONE | LP00907 | NCGC00024992-02 | 1-phenyl-5-methyl-2-pyridinone | DTXSID4045183 | NCGC00015806-05 | HMS3262F1
Storage
Room temperature
Shipped In
Normal
★
Size
USA
ドイツ (EU)*
Price
Qty
100mg
P129335-100mg
3 在庫あり
—
$9.90
250mg
P129335-250mg
5 在庫あり
—
$10.90
1g
P129335-1g
5 在庫あり
—
$15.90
5g
P129335-5g
3 在庫あり
—
$29.90
25g
P129335-25g
1 在庫あり
—
$94.90
100g
P129335-100g
2 在庫あり
—
$339.90
Enter a quantity for the sizes you want to add.
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♡ ウィッシュリスト ⇅ 比較リストに入れる ⎙ Print page
SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
概要 Specifications 製品の性質 名前と識別子 Documentation Advanced Data Taxonomic Classification 3 D構造 関連ターゲット（人間） 関連ターゲット（非人間） 作用メカニズム 証明書（CoA、COO、BSE/TSEと分析図） 化学的性質と物理的性質 よくある質問と記事 Citations of This Product ソリューション計算機 レビュー
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Why this grade

Moligand™, ≥98%(GC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 19 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

概要

Application：

Pyrfenidone is used for:
1、 As a postoperative eye drop for rabbits, analyze its anti fibrotic effect and improve glaucoma filtration surgery.
2、As an anti scarring agent, check if it affects the foreign body reaction after implantation of glaucoma drainage device (GDD) in rabbits.
3、Test its anti fibrotic potential in primary culture of human orbital fibroblasts (hOF).
4、 As tumor necrosis factor (TNF) α） Inhibitors, studying their role in hypoxia.

Explanation：

Pyrfenidone (5-methyl-1-phenyl-2- [1H] - pyridone) is a synthesized pyridine derivative.

Specifications

同義語
MFCD00866047 | Pirfenidona [INN-Spanish] | PIRFENIDONE [INN] | Pirfenidone(AMR69) | 5-Methyl-1-phenyl-2(1H)-pyridone | ESBRIET COMPONENT PIRFENIDONE | LP00907 | NCGC00024992-02 | 1-phenyl-5-methyl-2-pyridinone | DTXSID4045183 | NCGC00015806-05 | HMS3262F1
仕様と純度
Moligand™, ≥98%(GC)
生化学的・生理学的メカニズム
Pirfenidone inhibits collagen production and fibroblast proliferation. It has shown antifibrotic and anti-inflammatory properties in variety of animal models of pulmonary fibrosis, and in clinical trials.Orally active anti-inflammatory, antifibrotic and a
保管条件
Room temperature
入荷
Normal
等級
Moligand™
アクションタイプ
INHIBITOR
注
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
純度
≥98%(GC)
製品の性質
ALogP1.9
名前と識別子
パブケム・シド488183324
パブケム・シド・ウルhttps://pubchem.ncbi.nlm.nih.gov/substance/488183324
カノニカル・スマイルCC1=CN(C(=O)C=C1)C2=CC=CC=C2
IUPAC Name5-methyl-1-phenylpyridin-2-one
InChIKeyISWRGOKTTBVCFA-UHFFFAOYSA-N
INCHI1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3
異性体SMILES CC1=CN(C(=O)C=C1)C2=CC=CC=C2
WGKドイツ 3
RTECS UV1148200
分子量 185.22
Beilstein 21(5)7,197
Reaxy-Rn 1526549
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1526549&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
分類Pyridines and derivatives
SubclassHydropyridines
Intermediate Tree Nodes Not available
Direct ParentPyridinones
Alternative Parents Methylpyridines  Dihydropyridines  Benzene and substituted derivatives  Heteroaromatic compounds  Lactams  Azacyclic compounds  Organopnictogen compounds  Organooxygen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Dihydropyridine - Pyridinone - Methylpyridine - Monocyclic benzene moiety - Benzenoid - Heteroaromatic compound - Lactam - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic oxygen compound - Aromatic heteromonocyclic compound
説明This compound belongs to the class of organic compounds known as pyridinones. These are compounds containing a pyridine ring, which bears a ketone.
External Descriptors ring assembly - pyridone
3 D構造
インタラクティブ化学構造モデル





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作用メカニズム
証明書（CoA、COO、BSE/TSEと分析図）
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

45 results found

Lot NumberCertificate Type日付商品
G2630538Certificate of AnalysisJul 21, 2026 P129335
G2630537Certificate of AnalysisJul 21, 2026 P129335
G2630536Certificate of AnalysisJul 21, 2026 P129335
G2630535Certificate of AnalysisJul 21, 2026 P129335
G2630534Certificate of AnalysisJul 21, 2026 P129335
G2610035Certificate of AnalysisJul 15, 2026 P129335
K2526079Certificate of AnalysisAug 27, 2025 P129335
I2508599Certificate of AnalysisAug 27, 2025 P129335
I2508598Certificate of AnalysisAug 27, 2025 P129335
I2508597Certificate of AnalysisAug 27, 2025 P129335
D2601052Certificate of AnalysisAug 27, 2025 P129335
A1612032Certificate of AnalysisMar 04, 2025 P129335
B2108105Certificate of AnalysisSep 04, 2024 P129335
F2520040Certificate of AnalysisJul 10, 2024 P129335
C2518069Certificate of AnalysisJul 10, 2024 P129335
G2425684Certificate of AnalysisJul 10, 2024 P129335
G2425654Certificate of AnalysisJul 10, 2024 P129335
G2425653Certificate of AnalysisJul 10, 2024 P129335
G2425652Certificate of AnalysisJul 10, 2024 P129335
K2011046Certificate of AnalysisJun 17, 2024 P129335
K2011044Certificate of AnalysisJun 17, 2024 P129335
F2218062Certificate of AnalysisApr 02, 2024 P129335
F2218063Certificate of AnalysisApr 02, 2024 P129335
G23261370Certificate of AnalysisJul 07, 2023 P129335
G2326919Certificate of AnalysisJul 07, 2023 P129335
G2326916Certificate of AnalysisJul 07, 2023 P129335
G2326915Certificate of AnalysisJul 07, 2023 P129335
G2326913Certificate of AnalysisJul 07, 2023 P129335
G2326912Certificate of AnalysisJul 07, 2023 P129335
G23261374Certificate of AnalysisJul 07, 2023 P129335
G2326908Certificate of AnalysisJul 07, 2023 P129335
G2326909Certificate of AnalysisJul 07, 2023 P129335
G2326927Certificate of AnalysisJul 07, 2023 P129335
I2226090Certificate of AnalysisJul 18, 2022 P129335
I2226094Certificate of AnalysisJul 18, 2022 P129335
I2226093Certificate of AnalysisJul 18, 2022 P129335
I2226092Certificate of AnalysisJul 18, 2022 P129335
I2226091Certificate of AnalysisJul 18, 2022 P129335
D2321339Certificate of AnalysisJul 18, 2022 P129335
D2324141Certificate of AnalysisJul 18, 2022 P129335
C2020021Certificate of AnalysisJan 25, 2022 P129335
B2216011Certificate of AnalysisDec 08, 2021 P129335
B2216010Certificate of AnalysisDec 08, 2021 P129335
F2218061Certificate of AnalysisDec 08, 2021 P129335
B2215427Certificate of AnalysisDec 08, 2021 P129335
化学的性質と物理的性質
溶解度Soluble in water (>10 mg/ml at 60 °C), chloroform, DMSO (>20 mg/ml), ethanol, and DMF.
融点（°C）107.0 to 111.0 °C
分子量185.220 g/mol
XLogP31.900
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count1
Exact Mass185.084 Da
Monoisotopic Mass185.084 Da
Topological Polar Surface Area20.300 Ų
Heavy Atom Count14
Formal Charge0
Complexity285.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
よくある質問と記事
Pyridinones as “Property Knobs” in Drug Design: From Tautomers and H-Bonding Fingerprints to Product Selection (Tables A–C)
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
Tags:
pyridinone Drug Design
Roles and Mechanisms of Proteases in Respiratory and Vascular Diseases
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
Tags:
proteases respiratory diseases vascular diseases neutrophil elastase matrix metalloproteinases cathepsins protease-activated receptors airway remodeling plaque stability vascular remodeling
Citations of This Product
How to Cite Aladdin Scientific Products? Citations Search
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