Piromelatine - ≥99% , Melatonin receptor agonist, CAS No.946846-83-9, Melatonin receptor agonist

CAS: 946846-83-9 Cat. No.: P649870 分子式: C17H16N2O4 分子量: 312.32 PubChem CID: 24815904
注文可能
GRADE & PURITY ≥99%
Synonyms
Piromelatine [INN] | NEU-P11 | NEU-P-11 | Piromelatine | S3UN2146K9 | N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)-4-oxo-4H-pyran-2-carboxamide
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
USA
ドイツ (EU)*
Price
Qty
1mg
P649870-1mg
1 在庫あり
—
$99.90
5mg
P649870-5mg
1 在庫あり
—
$199.90
10mg
P649870-10mg
1 在庫あり
—
$313.90
25mg
P649870-25mg
1 在庫あり
—
$625.90
50mg
P649870-50mg
1 在庫あり
—
$999.90
100mg
P649870-100mg
1 在庫あり
—
$1,599.90
Enter a quantity for the sizes you want to add.
🧪
Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

概要

Piromelatine (Neu-P11) is a melatonin MT1/MT2 receptor agonist, serotonin 5-HT1A/5-HT1D agonist, and serotonin 5-HT2B antagonist. Piromelatine (Neu-P11) possesses sleep promoting, analgesic, anti-neurodegenerative, anxiolytic and antidepressant potentials. Piromelatine (Neu-P11) also possesses pain-related P2X3, TRPV1, and Nav1.7 channel-inhibition capacities

Specifications

同義語
Piromelatine [INN] | NEU-P11 | NEU-P-11 | Piromelatine | S3UN2146K9 | N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)-4-oxo-4H-pyran-2-carboxamide
仕様と純度
≥99%
保管条件
Protected from light,Store at -20°C
入荷
Ice chest + Ice pads
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
アクションタイプ
AGONIST
作用メカニズム
Melatonin receptor agonist
純度
≥99%
製品の性質
ALogP
1.7
名前と識別子
パブケム・シド
カノニカル・スマイル
COC1=CC2=C(C=C1)NC=C2CCNC(=O)C3=CC(=O)C=CO3
IUPAC Name
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxopyran-2-carboxamide
InChIKey
PNTNBIHOAPJYDB-UHFFFAOYSA-N
INCHI
1S/C17H16N2O4/c1-22-13-2-3-15-14(9-13)11(10-19-15)4-6-18-17(21)16-8-12(20)5-7-23-16/h2-3,5,7-10,19H,4,6H2,1H3,(H,18,21)
異性体SMILES
COC1=CC2=C(C=C1)NC=C2CCNC(=O)C3=CC(=O)C=CO3
代替CAS番号
946846-83-9
PubChem CID
24815904
MeSH用語
N-(2-(5-methoxy-indol-3-yl)-ethyl)-4-oxo-4H-pyran-2-carboxamide;Neu-P11;piromelatine
分子量
312.32

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
分類Indoles and derivatives
SubclassIndoles
Intermediate Tree Nodes Not available
Direct Parent3-alkylindoles
Alternative Parents Anisoles  2-heteroaryl carboxamides  Pyranones and derivatives  Alkyl aryl ethers  Substituted pyrroles  Heteroaromatic compounds  Secondary carboxylic acid amides  Cyclic ketones  Oxacyclic compounds  Azacyclic compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents 3-alkylindole - 2-heteroaryl carboxamide - Anisole - Phenol ether - Alkyl aryl ether - Pyranone - Pyran - Benzenoid - Substituted pyrrole - Heteroaromatic compound - Pyrrole - Carboxamide group - Cyclic ketone - Secondary carboxylic acid amide - Carboxylic acid derivative - Ether - Oxacycle - Azacycle - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Aromatic heteropolycyclic compound
説明This compound belongs to the class of organic compounds known as 3-alkylindoles. These are compounds containing an indole moiety that carries an alkyl chain at the 3-position.
External Descriptors Not available
3 D構造
インタラクティブ化学構造モデル





作用メカニズム
証明書(CoA、COO、BSE/TSEと分析図)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot NumberCertificate Type日付商品
J2423605Certificate of AnalysisJul 09, 2024 P649870
J2423611Certificate of AnalysisJul 09, 2024 P649870
J2423614Certificate of AnalysisJul 09, 2024 P649870
J2423615Certificate of AnalysisJul 09, 2024 P649870
J2423617Certificate of AnalysisJul 09, 2024 P649870
J2423619Certificate of AnalysisJul 09, 2024 P649870
J2423621Certificate of AnalysisJul 09, 2024 P649870
J2423624Certificate of AnalysisJul 09, 2024 P649870
J2423625Certificate of AnalysisJul 09, 2024 P649870
J2423626Certificate of AnalysisJul 09, 2024 P649870
J2423628Certificate of AnalysisJul 09, 2024 P649870
J2423630Certificate of AnalysisJul 09, 2024 P649870
化学的性質と物理的性質
溶解度DMSO : 250 mg/mL (800.46 mM; Need ultrasonic)
感度Light sensitive
分子量312.320 g/mol
XLogP31.700
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass312.111 Da
Monoisotopic Mass312.111 Da
Topological Polar Surface Area80.400 Ų
Heavy Atom Count23
Formal Charge0
Complexity529.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
ソリューション計算機
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