Poly(D,L-lactide) - ester terminated, 0.55-0.75 dL/g , CAS No.26680-10-4

CAS: 26680-10-4 Cat. No.: P299057

GRADE & PURITY ester terminated, 0.55-0.75 dL/g

Synonyms

3,6-Dimethyl-1,4-dioxane-2,5-dione|DL-Lactide|95-96-5|LACTIDE|Dilactide|1,4-Dioxane-2,5-dione, 3,6-dimethyl-|3,6-Dimethyl-2,5-dioxo-1,4-dioxane|DL-Dilactide|p-Dioxane-2,5-dione, 3,6-dimethyl-|Lactic acid, bimol. cyclic ester|26680-10-4|rac-lactide|UNII-7E

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

Biodegradable, biocompatible, and bioresorbable polymer composed of D,L-Lactide. This amorphous material has been used in sustained release drug delivery applications, by improving targeting and offering precise delivery timing. Degradation of this material has been thoroughly studied and has been shown to be safely resorbed by the body after implantation or injection. Modification of molecular weight and polymer composition allows for control of the degradation rate and mechanical stability of the polymer.

Specifications

Synonyms

3, 6-Dimethyl-1, 4-dioxane-2, 5-dione | DL-Lactide | 95-96-5 | LACTIDE | Dilactide | 1, 4-Dioxane-2, 5-dione, 3, 6-dimethyl- | 3, 6-Dimethyl-2, 5-dioxo-1, 4-dioxane | DL-Dilactide | p-Dioxane-2, 5-dione, 3, 6-dimethyl- | Lactic acid, bimol. cyclic ester | 26680-10-4 | rac-lactide | UNII-7E

Specifications & Purity

ester terminated, 0.55-0.75 dL/g

Legal Information

RESOMER is a registered trademark of Evonik Rohm GmbH

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: CC1C(=O)OC(C(=O)O1)C
• IUPAC Name: 3,6-dimethyl-1,4-dioxane-2,5-dione
• InChIKey: JJTUDXZGHPGLLC-UHFFFAOYSA-N
• INCHI: 1S/C6H8O4/c1-3-5(7)10-4(2)6(8)9-3/h3-4H,1-2H3
• Isomeric SMILES: CC1C(=O)OC(C(=O)O1)C
• Reaxy-Rn: 82121
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=82121&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Dioxanes
      • Subclass 1,4-dioxanes

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Dioxanes
• Subclass: 1,4-dioxanes
• Intermediate Tree Nodes: Not available
• Direct Parent: 1,4-dioxanes
• Alternative Parents: Dicarboxylic acids and derivatives Lactones Carboxylic acid esters Oxacyclic compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Dicarboxylic acid or derivatives - Para-dioxane - Lactone - Carboxylic acid ester - Oxacycle - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as 1,4-dioxanes. These are organic compounds containing 1,4-dioxane, an aliphatic six-member ring with two oxygen atoms in ring positions 1 and 4.
• External Descriptors: a small molecule

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Molecular Weight: 144.120 g/mol
• XLogP3: 0.600
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 144.042 Da
• Monoisotopic Mass: 144.042 Da
• Topological Polar Surface Area: 52.600 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 155.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 2
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Chenyang Cai, Yongqin Wang, Zechang Wei, Yu Fu.  (2021)  Biomimetic 3D Membranes with MXene Heterostructures for Superior Solar Steam Generation, Water Treatment, and Electricity Generation.  Solar RRL,  5  (11): (2100593).  [PMID:] [10.1002/solr.202100593]

2. Hao Zhang, Yilin Dong, Keke Huang, Jingsheng Liu, Bo Dong, Feng Wang.  (2019)  Immortal Ring Opening Polymerization of ε-caprolactone and rac-lactide by magnesium precatalysts bearing sterically congested phenoxide ligands.  EUROPEAN POLYMER JOURNAL,      [PMID:] [10.1016/j.eurpolymj.2019.06.029]