Polydatin - ≥95%(HPLC) , CAS No.27208-80-6

CAS: 27208-80-6 Cat. No.: P109978 分子式: C₂₀H₂₂O₈ 分子量: 390.39 Beilstein Registry Number: 17(4)3001 EC番号: 111-790-2

GRADE & PURITY ≥95%(HPLC)

Synonyms

Piceid | Resveratrol 3-Glucoside | 4',5-Dihydroxystilben-3-yl β-D-Glucopyranoside

Storage

Store at 2-8°C

Shipped In

Wet ice

概要

Polydatin is the glycoside of Resveratrol originally isolated from the Chinese herb Polygonum cuspidatum. The compound has been shown to inhibit platelet aggregation and elevate the ratios of LDL-C/HDL-C and TC/HDL-C. Myocardial cell, white blood cell, vascular smooth muscle cell, and endothelial cell studies report that Polydatin can inhibit ICAM-1 expression, elevate Ca2+, weaken white blood cell-endothelial cell adhesion, and activate KATP channels.
Polydatin, a type of polyphenolic phytoalexin, has many physiological and pharmacological effects including anti-inflammatory and anti-oxidative activities.

Specifications

同義語

Piceid | Resveratrol 3-Glucoside | 4',5-Dihydroxystilben-3-yl β-D-Glucopyranoside

仕様と純度

≥95%(HPLC)

生化学的・生理学的メカニズム

Stilbene found in medicinal herbs. Antioxidant, anti-inflammatory and neuroprotective.Inhibits LPS induced ICAM1 and NF-kB. Resveratrol precursor and Dihydroresveratrol ( Asc 2862 ) derivative. Anti-inflammatory, anti-ischemic, neuroprotective and antisep

保管条件

Store at 2-8°C

入荷

Wet ice

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

ACTIVATOR

注

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

純度

≥95%(HPLC)

名前と識別子

パブケム・シド

504763382

パブケム・シド・ウル

https://pubchem.ncbi.nlm.nih.gov/substance/504763382

カノニカル・スマイル

C1=CC(=CC=C1C=CC2=CC(=CC(=C2)OC3C(C(C(C(O3)CO)O)O)O)O)O

IUPAC Name

(2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol

InChIKey

HSTZMXCBWJGKHG-CUYWLFDKSA-N

INCHI

1S/C20H22O8/c21-10-16-17(24)18(25)19(26)20(28-16)27-15-8-12(7-14(23)9-15)2-1-11-3-5-13(22)6-4-11/h1-9,16-26H,10H2/b2-1+/t16-,17-,18+,19-,20-/m1/s1

異性体SMILES

C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O

代替CAS番号

65914-17-2

分子量

390.39

Beilstein

17(4)3001

Reaxy-Rn

1604738

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1604738&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • 分類 Stilbenes
      • Subclass Stilbene glycosides

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• 分類: Stilbenes
• Subclass: Stilbene glycosides
• Intermediate Tree Nodes: Not available
• Direct Parent: Stilbene glycosides
• Alternative Parents: Phenolic glycosides Hexoses O-glycosyl compounds Styrenes Phenoxy compounds Phenol ethers 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Oxanes Secondary alcohols Polyols Oxacyclic compounds Acetals Primary alcohols Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Stilbene glycoside - Phenolic glycoside - Hexose monosaccharide - Glycosyl compound - O-glycosyl compound - Phenoxy compound - Styrene - Phenol ether - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Monocyclic benzene moiety - Monosaccharide - Benzenoid - Oxane - Secondary alcohol - Acetal - Oxacycle - Organoheterocyclic compound - Polyol - Alcohol - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Organic oxygen compound - Aromatic heteromonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as stilbene glycosides. These are compounds structurally characterized by the presence of a carbohydrate moiety glycosidically linked to the stilbene skeleton.
• External Descriptors: Diphenyl ethers, biphenyls, dibenzyls and stilbenes

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)

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HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)

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作用メカニズム

化学的性質と物理的性質

• 溶解度: Soluble in water (<1 mg/ml at 25 °C), DMSO (78 mg/ml at 25 °C), ethanol (<1 mg/ml at 25 °C), methanol, and ethyl acetate.
• 感度: Heat sensitive
• 比旋光度［α］: -54 ° (C=1, Acetone)
• 融点（°C）: 223-226°C
• 分子量: 390.400 g/mol
• XLogP3: 1.700
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 5
• Exact Mass: 390.131 Da
• Monoisotopic Mass: 390.131 Da
• Topological Polar Surface Area: 140.000 Ų
• Heavy Atom Count: 28
• Formal Charge: 0
• Complexity: 506.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 5
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1