PROTAC SMARCA2/4-degrader-9 (Compound I-503) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2 and SMARCA4. PROTAC SMARCA2 degrader-9 degrades SMARCA2 in MV411 and in A549 with DC 50 <100 nM, degrades SMARCA4 in MV411 with DC 50 <100 nM. (Pink: Ligand for target protein ; Black: Linker ; Blue: Ligand for E3 ligase (S,R,S)-AHPC )
Specifications
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
DEGRADER
Names and Identifiers
Molecular Weight
914.13
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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Reviews
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