グレード＆純度Animal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Bioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.His Tag?His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein.≥95%(SDS-PAGE)
Accession #
Q12918
Protein Tag
C-His
Expression system
HEK293
Endotoxin Concentration
<0.1 EU/μg
Bioactivity
Immobilized Human CD161, His Tag at 2 μg/mL (100 μL/Well) on the plate. Dose response curve for Anti-CD161 Antibody, hFc Tag with the EC50 of 5.3ng/mL determined by ELISA.
C-type lectin domain family 5 member B | HNKR-P1a | Natural killer cell surface protein P1A | NKR-P1A | CD161 antigen | CD161 | CLEC5B | C-type lectin domain family 5 member B | HNKR-P1a | killer cell lectin-like receptor subfamily B member 1 | killer cel
等級
ActiBioPure™, Animal Free, Bioactive, Carrier Free, His Tag
仕様と純度
Animal Free, Carrier Free, Bioactive, ActiBioPure™, His Tag, ≥95%(SDS-PAGE)
生化学的・生理学的メカニズム
Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinas
生物活性
Immobilized Human CD161, His Tag at 2 μg/mL (100 μL/Well) on the plate. Dose response curve for Anti-CD161 Antibody, hFc Tag with the EC50 of 5.3ng/mL determined by ELISA.
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
保管条件
Store at -20°C,Avoid repeated freezing and thawing
入荷
Ice chest + Ice pads
安定性と保管
Store at -20~-80℃ long term (1 year). Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.
画像
Recombinant Human CD161 Protein (rp143822) - Protein Bioactivity
Immobilized Human CD161 Protein at 1.0 μg/mL can bind CD161 Mouse mAb (Ab094006) with the EC50 of 352.3 ng/mL.
Recombinant Human CD161 Protein (rp143822) - SDS-PAGE
2 μg/lane of Recombinant Human CD161 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 38 kDa.
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
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