Ruscogenin - Moligand™, 10mM in DMSO , CAS No.472-11-7

CAS: 472-11-7 Cat. No.: R424112 分子式: C27H42O4 分子量: 430.62 EC番号: 207-447-2 PubChem CID: 441893
注文可能
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
Ruscogenin, >=98% (HPLC) | RUSCOGENIN [MART.] | EINECS 207-447-2 | Ruscogenin | S9183 | CCG-269015 | BXI92R2VUJ | C08909 | RUSCOGENIN [INCI] | Z2037319104 | (25R)-Spirost-5-ene-1beta,3beta-diol | Q27108184 | (25R)-SPIROST-5-ENE-1.BETA.,3.BETA.-DIOL | 5-Ch
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
USA
ドイツ (EU)*
Price
Qty
1ml
R424112-1ml
1 在庫あり
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$78.90
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

概要

Product Describtion:

Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway and exerts significant anti-inflammatory and anti-thrombotic activities.


Specifications

同義語
Ruscogenin, >=98% (HPLC) | RUSCOGENIN [MART.] | EINECS 207-447-2 | Ruscogenin | S9183 | CCG-269015 | BXI92R2VUJ | C08909 | RUSCOGENIN [INCI] | Z2037319104 | (25R)-Spirost-5-ene-1beta,3beta-diol | Q27108184 | (25R)-SPIROST-5-ENE-1.BETA.,3.BETA.-DIOL | 5-Ch
仕様と純度
Moligand™, 10mM in DMSO
生化学的・生理学的メカニズム
Ruscogenin inhibits the expressions of TF, iNOS, and NF-kappaB p65 and is therefore a potential target for acute lung injury or sepsis.
保管条件
Store at -80°C
入荷
Dry ice packs + Cold packs
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
等級
Moligand™
アクションタイプ
INHIBITOR
名前と識別子
パブケム・シド528775147
パブケム・シド・ウルhttps://pubchem.ncbi.nlm.nih.gov/substance/528775147
カノニカル・スマイルCC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(C(CC(C6)O)O)C)C)C)OC1
IUPAC Name(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,14R,16R)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-14,16-diol
InChIKeyQMQIQBOGXYYATH-IDABPMKMSA-N
INCHI1S/C27H42O4/c1-15-7-10-27(30-14-15)16(2)24-22(31-27)13-21-19-6-5-17-11-18(28)12-23(29)26(17,4)20(19)8-9-25(21,24)3/h5,15-16,18-24,28-29H,6-14H2,1-4H3/t15-,16+,18-,19-,20+,21+,22+,23-,24+,25+,26+,27-/m1/s1
異性体SMILES C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5([C@@H](C[C@@H](C6)O)O)C)C)C)OC1
PubChem CID 441893
分子量 430.62

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3 D構造
インタラクティブ化学構造モデル





関連ターゲット(人間)
BXPC-3 (2997 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THP-1 (11052 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
作用メカニズム
証明書(CoA、COO、BSE/TSEと分析図)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
化学的性質と物理的性質
分子量430.600 g/mol
XLogP34.700
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass430.308 Da
Monoisotopic Mass430.308 Da
Topological Polar Surface Area58.900 Ų
Heavy Atom Count31
Formal Charge0
Complexity779.000
Isotope Atom Count0
Defined Atom Stereocenter Count12
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
ソリューション計算機
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