SAK 3 - ≥98%(HPLC) , CAS No.1256269-87-0

CAS: 1256269-87-0 Cat. No.: S287847 分子式: C₂₀H₂₃N₃O₄ 分子量: 369.41 PubChem CID: 71655974

GRADE & PURITY ≥98%(HPLC)

Synonyms

Ethyl8'-methyl-2',4-dioxo-2-(piperidin-1-yl)-2'H-spiro[cyclopent[2]ene-1,3'-imidazo[1,2-a]pyridine]-3-carboxylate | YJ4M3A4ZH4 | SAK3, >=98% (HPLC) | SAK3 | SAK-3 | Spiro[2-cyclopentene-1,3'(2'H)-imidazo[1,2-a]pyridine]-3-carboxylic acid, 8'-methyl-2',4-d

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

同義語

Ethyl8'-methyl-2',4-dioxo-2-(piperidin-1-yl)-2'H-spiro[cyclopent[2]ene-1,3'-imidazo[1,2-a]pyridine]-3-carboxylate | YJ4M3A4ZH4 | SAK3, >=98% (HPLC) | SAK3 | SAK-3 | Spiro[2-cyclopentene-1,3'(2'H)-imidazo[1,2-a]pyridine]-3-carboxylic acid, 8'-methyl-2',4-d

仕様と純度

≥98%(HPLC)

生化学的・生理学的メカニズム

Potent CaV3.1 and CaV3.3 activator. Enhances CaV3.1 and CaV3.3, but not CaV3.2 activity at concentrations of 0.01 - 10 M in neuro2A cellsin vitro. Elevates ACh levels in hippocampus. Rescues impaired memory-related behaviors, promotes adult neurogenesis a

保管条件

Store at 2-8°C

入荷

Wet ice

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

純度

≥98%(HPLC)

名前と識別子

• カノニカル・スマイル: CCOC(=O)C1=C(C2(CC1=O)C(=O)N=C3N2C=CC=C3C)N4CCCCC4
• IUPAC Name: ethyl 8'-methyl-2',5-dioxo-2-piperidin-1-ylspiro[cyclopentene-3,3'-imidazo[1,2-a]pyridine]-1-carboxylate
• InChIKey: WZHBYTVHUFURPY-UHFFFAOYSA-N
• INCHI: 1S/C20H23N3O4/c1-3-27-18(25)15-14(24)12-20(16(15)22-9-5-4-6-10-22)19(26)21-17-13(2)8-7-11-23(17)20/h7-8,11H,3-6,9-10,12H2,1-2H3
• 異性体SMILES: CCOC(=O)C1=C(C2(CC1=O)C(=O)N=C3N2C=CC=C3C)N4CCCCC4
• PubChem CID: 71655974
• 分子量: 369.41

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 分類 Imidazopyridines
      • Subclass Imidazopyridinones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 分類: Imidazopyridines
• Subclass: Imidazopyridinones
• Intermediate Tree Nodes: Not available
• Direct Parent: Imidazopyridinones
• Alternative Parents: Alpha amino acids and derivatives Dihydropyridines Pyridinones Imidazolinones Piperidines Vinylogous amides Enoate esters N-acylimines Trialkylamines Cyclic ketones Monocarboxylic acids and derivatives Enamines Carboximidamides Carboxamidines Azacyclic compounds Propargyl-type 1,3-dipolar organic compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteropolycyclic compounds
• Substituents: Alpha-amino acid or derivatives - Imidazopyridinone - Dihydropyridine - Pyridinone - Imidazolinone - Piperidine - 2-imidazoline - Vinylogous amide - Alpha,beta-unsaturated carboxylic ester - Enoate ester - Amino acid or derivatives - Carboxylic acid ester - Ketone - Tertiary amine - Tertiary aliphatic amine - N-acylimine - Cyclic ketone - Carboxylic acid amidine - Carboximidamide - Monocarboxylic acid or derivatives - Amidine - Azacycle - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Enamine - Carboxylic acid derivative - Organooxygen compound - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Amine - Carbonyl group - Organonitrogen compound - Aliphatic heteropolycyclic compound
• 説明: This compound belongs to the class of organic compounds known as imidazopyridinones. These are compounds containing an imidazopyridine moiety where the pyridine ring bears a ketone group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

化学的性質と物理的性質

• 溶解度: Solvent:DMSO, Max Conc. mg/mL: 36.94, Max Conc. mM: 100; Solvent:1eq. HCl, Max Conc. mg/mL: 36.94, Max Conc. mM: 100
• 分子量: 369.400 g/mol
• XLogP3: 1.400
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 369.169 Da
• Monoisotopic Mass: 369.169 Da
• Topological Polar Surface Area: 79.300 Ų
• Heavy Atom Count: 27
• Formal Charge: 0
• Complexity: 845.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

よくある質問

What is the purity of this product, and how is it determined?

This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1256269-87-0, the molecular formula is C??H??N?O?, and the molecular weight is 369.41 g/mol. InChIKey WZHBYTVHUFURPY-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.