SCR7 pyrazine - ≥98%(HPLC) , CAS No.14892-97-8

CAS: 14892-97-8 Cat. No.: S287286 Molecular Weight: 332.38 EC Number: 998-871-3 PubChem CID: 10688007

GRADE & PURITY ≥98%(HPLC)

Synonyms

SCR7 pyrazine, >=98% (HPLC) | HY-107845 | Z3244609139 | 6,7-diphenyl-2-thioxo-2,3-dihydropteridin-4(1H)-one | AKOS025404699 | SCR7 pyrazine | 6,7-diphenyl-2-sulfanylpteridin-4-ol | Oprea1_571617 | 6,7-diphenyl-2-sulfanyl-3H-pteridin-4-one | GM-0028 | SCHE

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Synonyms

SCR7 pyrazine, >=98% (HPLC) | HY-107845 | Z3244609139 | 6, 7-diphenyl-2-thioxo-2, 3-dihydropteridin-4(1H)-one | AKOS025404699 | SCR7 pyrazine | 6, 7-diphenyl-2-sulfanylpteridin-4-ol | Oprea1_571617 | 6, 7-diphenyl-2-sulfanyl-3H-pteridin-4-one | GM-0028 | SCHE

Specifications & Purity

≥98%(HPLC)

Biochemical and Physiological Mechanisms

Enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiencyin vitroup to 19-fold. Inhibits nonhomologous end-joining (NHEJ).

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%(HPLC)

Names and Identifiers

• Pubchem Sid: 504765581
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504765581
• Canonical Smiles: C1=CC=C(C=C1)C2=NC3=C(NC(=S)NC3=O)N=C2C4=CC=CC=C4
• IUPAC Name: 6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one
• InChIKey: GSRTWXVBHGOUBU-UHFFFAOYSA-N
• INCHI: 1S/C18H12N4OS/c23-17-15-16(21-18(24)22-17)20-14(12-9-5-2-6-10-12)13(19-15)11-7-3-1-4-8-11/h1-10H,(H2,20,21,22,23,24)
• Isomeric SMILES: C1=CC=C(C=C1)C2=NC3=C(NC(=S)NC3=O)N=C2C4=CC=CC=C4
• PubChem CID: 10688007
• Molecular Weight: 332.38

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Pteridines and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Pteridines and derivatives
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Pteridines and derivatives
• Alternative Parents: Pyrimidones Pyrimidinethiones 2-Thiopyrimidines Pyrazines Benzene and substituted derivatives Vinylogous amides Heteroaromatic compounds Thioureas Lactams Azacyclic compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Pteridine - 2-thiopyrimidine - Thiopyrimidine - Pyrimidone - Pyrimidinethione - Monocyclic benzene moiety - Pyrazine - Benzenoid - Pyrimidine - Heteroaromatic compound - Vinylogous amide - Lactam - Thiourea - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as pteridines and derivatives. These are polycyclic aromatic compounds containing a pteridine moiety, which consists of a pyrimidine fused to a pyrazine ring to form pyrimido(4,5-b)pyrazine.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Solvent:DMSO, Max Conc. mg/mL: 33.44, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 6.69, Max Conc. mM: 20
• Sensitivity: Heat Sensitive
• Melt Point(°C): 209 °C
• Molecular Weight: 332.400 g/mol
• XLogP3: 2.900
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 332.073 Da
• Monoisotopic Mass: 332.073 Da
• Topological Polar Surface Area: 99.000 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 487.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1