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· · COA & SDS すべての製品に適用 · 在庫品は当日出荷 SIB 1757 - Moligand™, 10mM in DMSO , Allosteric modulator of mGlu 5 receptor, CAS No.31993-01-8, Allosteric modulator of mGlu 5 receptor
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO Synonyms
NCGC00185991-01 | CHEBI:93722 | SR-01000076142-1 | BCP33033 | BDBM50478347 | DTXSID00425754 | EU-0101161 | CCG-205235 | GTPL1431 | s2645 | MLS000860049 | L000560 | SIB1757 | SIB-1757 | SIB-1757; SIB1757 | AKOS024456470 | NCGC00025047-03 | SCHEMBL179770 |
Shipped In
Dry ice packs + Cold packs
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Why this grade Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
概要 SIB-1757 is a highly selective and noncompetitive antagonist of mGlu5 receptor with an IC50 of 0.4 μM。
Specifications 同義語
NCGC00185991-01 | CHEBI:93722 | SR-01000076142-1 | BCP33033 | BDBM50478347 | DTXSID00425754 | EU-0101161 | CCG-205235 | GTPL1431 | s2645 | MLS000860049 | L000560 | SIB1757 | SIB-1757 | SIB-1757; SIB1757 | AKOS024456470 | NCGC00025047-03 | SCHEMBL179770 |
仕様と純度
Moligand™, 10mM in DMSO
生化学的・生理学的メカニズム
A highly selective antagonist for the mGlu5metabotropic glutamate receptor subtype; displays an IC50value of 0.4μM at hmGlu5compared with > 30μM at hmGlu1b, hmGlu2, hmGlu4, hmGlu6, hmGlu7and hmGlu8.
入荷
Dry ice packs + Cold packs
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
アクションタイプ
ALLOSTERIC MODULATOR
作用メカニズム
Allosteric modulator of mGlu 5 receptor
名前と識別子 カノニカル・スマイル
CC1=NC(=C(C=C1)O)N=NC2=CC=CC=C2
IUPAC Name
6-methyl-2-phenyldiazenylpyridin-3-ol
InChIKey
LOCPVWIREQIGNQ-UHFFFAOYSA-N
INCHI
1S/C12H11N3O/c1-9-7-8-11(16)12(13-9)15-14-10-5-3-2-4-6-10/h2-8,16H,1H3
異性体SMILES
CC1=NC(=C(C=C1)O)N=NC2=CC=CC=C2
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds 分類 Pyridines and derivatives Subclass Methylpyridines Intermediate Tree Nodes Not available Direct Parent Methylpyridines Alternative Parents Hydroxypyridines Benzene and substituted derivatives Heteroaromatic compounds Azo compounds Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Organooxygen compounds Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Methylpyridine - Hydroxypyridine - Benzenoid - Monocyclic benzene moiety - Heteroaromatic compound - Azo compound - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organic nitrogen compound - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound 説明 This compound belongs to the class of organic compounds known as methylpyridines. These are organic compounds containing a pyridine ring substituted at one or more positions by a methyl group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3 D構造 関連ターゲット（人間） 証明書（CoA、COO、BSE/TSEと分析図） 化学的性質と物理的性質 分子量 213.230 g/mol XLogP3 3.000 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 4 Rotatable Bond Count 2 Exact Mass 213.09 Da Monoisotopic Mass 213.09 Da Topological Polar Surface Area 57.800 Ų Heavy Atom Count 16 Formal Charge 0 Complexity 238.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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