Silybin - Moligand™, 10 mM in DMSO , CAS No.802918-57-6

CAS: 802918-57-6 Cat. No.: S1499820 分子式: C₂₅H₂₂O₁₀ 分子量: 482.44 EC番号: 806-403-5 PubChem CID: 3086637

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Silybin is a flavonolignan isolated from milk thistle ( Silybum marianum ) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

Specifications

仕様と純度

Moligand™, 10 mM in DMSO

保管条件

Protected from light,Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

名前と識別子

• 異性体SMILES: COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)[C@@H]4[C@H](C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
• PubChem CID: 3086637
• 分子量: 482.44

化学的性質と物理的性質

• 融点（°C）: 152-153° C

参考文献

1. Guanglu Wang, Yue Xin, Kaixin Ping, Xuhui Xu, Ying Sun, Xing Li, Xinying Guan, Jingquan Dong.  (2023)  Silybin mitigates chronic Avermectin exposure-induced intestinal damage and growth inhibition in carp.  ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,      [PMID:38135203] [10.1016/j.etap.2023.104351]

2. Pan En-Zhuang, Xin Yue, Li Xue-Qing, Wu Xin-Yu, Tan Xue-Lian, Dong Jing-Quan.  (2023)  Ameliorative effects of silybin against avermectin-triggered carp spleen mitochondrial dysfunction and apoptosis through inhibition of PERK-ATF4-CHOP signaling pathway.  FISH PHYSIOLOGY AND BIOCHEMISTRY,      [PMID:37542703] [10.1007/s10695-023-01228-y]

3. Qiang-Ming Li, Xiu-Rong Yang, Xue-Qiang Zha, Li-Hua Pan, Dan-Dan Zang, Feng-Yun Zhang, Jian-Ping Luo.  (2022)  Protective Effects of Three Flavonoids from Dendrobium huoshanense Flowers on Alcohol-Induced Hepatocyte Injury via Activating Nrf2 and Inhibiting NF-κB Pathways.  CHEMISTRY & BIODIVERSITY,  19  (8): (e202200471).  [PMID:35774029] [10.1002/cbdv.202200471]

4. Meirong Huo, Honglan Wang, Ying Zhang, Han Cai, Pan Zhang, Lingchao Li, Jianping Zhou, Tingjie Yin.  (2020)  Co-delivery of silybin and paclitaxel by dextran-based nanoparticles for effective anti-tumor treatment through chemotherapy sensitization and microenvironment modulation.  JOURNAL OF CONTROLLED RELEASE,      [PMID:32044390] [10.1016/j.jconrel.2020.02.017]

5. Yong Li, Youdong Zhou, Yinqiu Tan, Gang Deng.  (2025)  Anti-Inflammatory Treatment of Subarachnoid Hemorrhage by Self-Assembled Silymarin Nanoparticles.  Small Science,      [PMID:40657200] [10.1002/smsc.202400322]

よくある質問

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 802918-57-6, the molecular formula is C25H22O10, and the molecular weight is 482.44 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.