Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Protected from light,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 5 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Silybin is a flavonolignan isolated from milk thistle ( Silybum marianum ) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .
| Isomeric SMILES | COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)[C@@H]4[C@H](C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O |
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| PubChem CID | 3086637 |
| Molecular Weight | 482.44 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Melt Point(°C) | 152-153° C |
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| 1. Guanglu Wang, Yue Xin, Kaixin Ping, Xuhui Xu, Ying Sun, Xing Li, Xinying Guan, Jingquan Dong. (2023) Silybin mitigates chronic Avermectin exposure-induced intestinal damage and growth inhibition in carp. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, [PMID:38135203] [10.1016/j.etap.2023.104351] |
| 2. Pan En-Zhuang, Xin Yue, Li Xue-Qing, Wu Xin-Yu, Tan Xue-Lian, Dong Jing-Quan. (2023) Ameliorative effects of silybin against avermectin-triggered carp spleen mitochondrial dysfunction and apoptosis through inhibition of PERK-ATF4-CHOP signaling pathway. FISH PHYSIOLOGY AND BIOCHEMISTRY, [PMID:37542703] [10.1007/s10695-023-01228-y] |
| 3. Qiang-Ming Li, Xiu-Rong Yang, Xue-Qiang Zha, Li-Hua Pan, Dan-Dan Zang, Feng-Yun Zhang, Jian-Ping Luo. (2022) Protective Effects of Three Flavonoids from Dendrobium huoshanense Flowers on Alcohol-Induced Hepatocyte Injury via Activating Nrf2 and Inhibiting NF-κB Pathways. CHEMISTRY & BIODIVERSITY, 19 (8): (e202200471). [PMID:35774029] [10.1002/cbdv.202200471] |
| 4. Meirong Huo, Honglan Wang, Ying Zhang, Han Cai, Pan Zhang, Lingchao Li, Jianping Zhou, Tingjie Yin. (2020) Co-delivery of silybin and paclitaxel by dextran-based nanoparticles for effective anti-tumor treatment through chemotherapy sensitization and microenvironment modulation. JOURNAL OF CONTROLLED RELEASE, [PMID:32044390] [10.1016/j.jconrel.2020.02.017] |
| 5. Yong Li, Youdong Zhou, Yinqiu Tan, Gang Deng. (2025) Anti-Inflammatory Treatment of Subarachnoid Hemorrhage by Self-Assembled Silymarin Nanoparticles. Small Science, [PMID:40657200] [10.1002/smsc.202400322] |
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View Moligand™ grade guide →
