SKI-178 - 10mM in DMSO , CAS No.1259484-97-3

CAS: 1259484-97-3 Cat. No.: S421090 分子式: C₂₁H₂₂N₄O₄ 分子量: 394.4 EC番号: 162-793-0 PubChem CID: 1356476

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Information

SKI-178 is a potent inhibitor of sphingosine kinase-1 (SphK1) and SphK2. SKI-178 induces apoptosis in a CDK1-dependent manner in human acute myeloid leukemia cell lines.

Specifications

仕様と純度

10mM in DMSO

生化学的・生理学的メカニズム

SKI-178 is a potent inhibitor of sphingosine kinase-1 (SphK1) and SphK2. SKI-178 induces apoptosis in a CDK1-dependent manner in human acute myeloid leukemia cell lines.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

名前と識別子

• パブケム・シド: 528767114
• カノニカル・スマイル: CC(=NNC(=O)C1=CC(=NN1)C2=CC=C(C=C2)OC)C3=CC(=C(C=C3)OC)OC
• IUPAC Name: N-[1-(3,4-dimethoxyphenyl)ethylideneamino]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide
• InChIKey: GMFUWEBOUKIKRP-UHFFFAOYSA-N
• INCHI: 1S/C21H22N4O4/c1-13(15-7-10-19(28-3)20(11-15)29-4)22-25-21(26)18-12-17(23-24-18)14-5-8-16(27-2)9-6-14/h5-12H,1-4H3,(H,23,24)(H,25,26)
• 異性体SMILES: CC(=NNC(=O)C1=CC(=NN1)C2=CC=C(C=C2)OC)C3=CC(=C(C=C3)OC)OC
• PubChem CID: 1356476
• 分子量: 394.4