SLC-391 - Moligand™ , Inhibitor of AXL receptor tyrosine kinase;Inhibitor of MER proto-oncogene; tyrosine kinase;Inhibitor of TYRO3 protein tyrosine kinase, CAS No.1783825-18-2, Inhibitor of AXL receptor tyrosine kinase;Inhibitor of MER proto-oncogene; tyrosine kinase;Inhibitor of TYRO3 protein tyrosine kinase

CAS: 1783825-18-2 Cat. No.: S613619 PubChem CID: 118110201

グレード＆純度 Moligand™

Synonyms

2-Pyridinamine, 3-[5-(cyclopropylmethyl)-1,3,4-oxadiazol-2-yl]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]- | 2-Pyridinamine, 3-(5-(cyclopropylmethyl)-1,3,4-oxadiazol-2-yl)-5-(1-(4-piperidinyl)-1H-pyrazol-4-yl)- | example 3.7 [WO2015081257A2] | SCHEMBL16758475

Storage

Room temperature

仕様

同義語

2-Pyridinamine, 3-[5-(cyclopropylmethyl)-1,3,4-oxadiazol-2-yl]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]- | 2-Pyridinamine, 3-(5-(cyclopropylmethyl)-1,3,4-oxadiazol-2-yl)-5-(1-(4-piperidinyl)-1H-pyrazol-4-yl)- | example 3.7 [WO2015081257A2] | SCHEMBL16758475

仕様と純度

Moligand™

保管条件

Room temperature

等級

Moligand™

アクションタイプ

INHIBITOR

作用メカニズム

Inhibitor of AXL receptor tyrosine kinase;Inhibitor of MER proto-oncogene; tyrosine kinase;Inhibitor of TYRO3 protein tyrosine kinase

名前と識別子

カノニカル・スマイル

C1CC1Cc1nnc(o1)c1c(ncc(c1)c1cn(nc1)C1CCNCC1)N

IUPAC Name

3-[5-(cyclopropylmethyl)-1,3,4-oxadiazol-2-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine

InChIKey

JYVSYFGHYFXYBE-UHFFFAOYSA-N

INCHI

1S/C19H23N7O/c20-18-16(19-25-24-17(27-19)7-12-1-2-12)8-13(9-22-18)14-10-23-26(11-14)15-3-5-21-6-4-15/h8-12,15,21H,1-7H2,(H2,20,22)

異性体SMILES

C1CC1CC2=NN=C(O2)C3=C(N=CC(=C3)C4=CN(N=C4)C5CCNCC5)N

PubChem CID

118110201

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 分類 Pyridines and derivatives
      • Subclass Halopyridines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 分類: Pyridines and derivatives
• Subclass: Halopyridines
• Intermediate Tree Nodes: Not available
• Direct Parent: 2-halopyridines
• Alternative Parents: Piperidines Imidolactams Heteroaromatic compounds 1,3,4-oxadiazoles Propargyl-type 1,3-dipolar organic compounds Oxacyclic compounds Hydrazones Dialkylamines Azacyclic compounds Aldimines Organopnictogen compounds Organooxygen compounds Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: 2-halopyridine - Imidolactam - Piperidine - Heteroaromatic compound - Oxadiazole - Azole - 1,3,4-oxadiazole - Oxacycle - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Secondary amine - Hydrazone - Secondary aliphatic amine - Aldimine - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Imine - Amine - Aromatic heteromonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as 2-halopyridines. These are organic compounds containing a pyridine ring substituted at the 2-position by a halogen atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

関連ターゲット（人間）

TYRO3 Tchem Tyrosine-protein kinase receptor TYRO3 (0 Activities)

Discover Target: TYRO3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MERTK Tchem Tyrosine-protein kinase Mer (0 Activities)

Discover Target: MERTK

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AXL Tchem Tyrosine-protein kinase receptor UFO (0 Activities)

Discover Target: AXL

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)