Sofiniclin - 10mM in DMSO , Neuronal acetylcholine receptor; alpha4/beta2 agonist, CAS No.799279-80-4, Neuronal acetylcholine receptor; alpha4/beta2 agonist

CAS: 799279-80-4 Cat. No.: S655728 分子式: C₁₀H₁₁Cl₂N₃ 分子量: 244.12 PubChem CID: 10131048

グレード＆純度 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Sofiniclin (ABT 894), an agonist of nicotinic acetylcholine receptor (nAChR) , is used as a potential non-stimulant research for attention-deficit/hyperactivity disorder (ADHD).

In Vitro

Sofiniclin is more potent than ABT-089 at both receptor subtypes, with K i values of 1.9 nM for 125 I-α-conotoxinMII binding and of 1.3 nM for 125 I-epibatidine binding. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Sofiniclin (0.001 to 0.10 mg/kg, p.o.) produces significant reductions in LIDs compared to vehicle monkey . Sofiniclin (0.1 mg/kg) does not decrease LIDs in monkeys with severe nigrostriatal damage. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

仕様

仕様と純度

10mM in DMSO

生化学的・生理学的メカニズム

Sofiniclin (ABT 894), an agonist of nicotinic acetylcholine receptor (nAChR) , is used as a potential non-stimulant research for attention-deficit/hyperactivity disorder (ADHD).

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

AGONIST

作用メカニズム

Neuronal acetylcholine receptor; alpha4/beta2 agonist

製品の性質

ALogP

2

名前と識別子

異性体SMILES

C1[C@H]2CN(C[C@H]2N1)C3=CC(=C(N=C3)Cl)Cl

PubChem CID

10131048

分子量

244.12

よくある質問

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 799279-80-4, the molecular formula is C10H11Cl2N3, and the molecular weight is 244.12 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.