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SCN1A

説明Sodium channel protein type 1 subunit alpha

Gene and Protein Information

Gene ID6323
Uniprot Accession IDs P35498 E9PG49 Q16172 Q585T7 Q8IUJ6 Q96LA3 Q9C008
Ensembl ID ENSP00000303540
Symbol NAC1 SCN1 FEB3 FHM3 NAC1 SCN1 SMEI EIEE6 FEB3A HBSCI GEFSP2 Nav1.1
FamilyBelongs to the sodium channel (TC 1.A.1.10) family. Nav1.1/SCN1A subfamily.
Sequence
MEQTVLVPPGPDSFNFFTRESLAAIERRIAEEKAKNPKPDKKDDDENGPKPNSDLEAGKNLPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSALYILTPFNPLRKIAIKILVHSLFSMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKIIARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCIQWPPTNASLEEHSIEKNITVNYNGTLINETVFEFDWKSYIQDSRYHYFLEGFLDALLCGNSSDAGQCPEGYMCVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMIEQLKKQQEAAQQAATATASEHSREPSAAGRLSDSSSEASKLSSKSAKERRNRRKKRKQKEQSGGEEKDEDEFQKSESEDSIRRKGFRFSIEGNRLTYEKRYSSPHQSLLSIRGSLFSPRRNSRTSLFSFRGRAKDVGSENDFADDEHSTFEDNESRRDSLFVPRRHGERRNSNLSQTSRSSRMLAVFPANGKMHSTVDCNGVVSLVGGPSVPTSPVGQLLPEVIIDKPATDDNGTTTETEMRKRRSSSFHVSMDFLEDPSQRQRAMSIASILTNTVEELEESRQKCPPCWYKFSNIFLIWDCSPYWLKVKHVVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTDHFNNVLTVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVTLSLVELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKIASDCQLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLTVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDNEMNNLQIAVDRMHKGVAYVKRKIYEFIQQSFIRKQKILDEIKPLDDLNNKKDSCMSNHTAEIGKDLDYLKDVNGTTSGIGTGSSVEKYIIDESDYMSFINNPSLTVTVPIAVGESDFENLNTEDFSSESDLEESKEKLNESSSSSEGSTVDIGAPVEEQPVVEPEETLEPEACFTEGCVQRFKCCQINVEEGRGKQWWNLRRTCFRIVEHNWFETFIVFMILLSSGALAFEDIYIDQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGYQTYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCINTTTGDRFDIEDVNNHTDCLKLIERNETARWKNVKVNFDNVGFGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEESLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGMVFDFVTRQVFDISIMILICLNMVTMMVETDDQSEYVTTILSRINLVFIVLFTGECVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPNKVNPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFMEFEKLSQFAAALEPPLNLPQPNKLQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEERFMASNPSKVSYQPITTTLKRKQEEVSAVIIQRAYRRHLLKRTVKQASFTYNKNKIKGGANLLIKEDMIIDRINENSITEKTDLTMSTAACPPSYDRVTKPIVEKHEQEGKDEKAKGK
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Homologous gene and protein info.
SpeciesGene IDGene Symbol名前納税者番号Other Gene IDSources
Chimp459703SCN1Asodium voltage-gated channel alpha subunit 19598VGNC:14353OMA, EggNOG
Macaque704086SCN1Asodium voltage-gated channel alpha subunit 19544Inparanoid, OMA
Mouse20265Scn1asodium channel, voltage-gated, type I, alpha10090MGI:98246Inparanoid, OMA, EggNOG
Rat81574Scn1asodium voltage-gated channel alpha subunit 110116RGD:69364Inparanoid, OMA
Dog478775SCN1Asodium voltage-gated channel alpha subunit 19615VGNC:45915Inparanoid, OMA
Horse100052059SCN1Asodium voltage-gated channel alpha subunit 19796VGNC:22732Inparanoid, OMA
Cow529590SCN1Asodium voltage-gated channel alpha subunit 19913VGNC:34345Inparanoid, OMA
Opossum100016606SCN1Asodium voltage-gated channel alpha subunit 113616Inparanoid, OMA, EggNOG
Chicken771555SCN1Asodium voltage-gated channel alpha subunit 19031CGNC:56868Inparanoid, EggNOG
Xenopusscn1asodium channel, voltage gated, type I alpha subunit [Source:Xenbase;Acc:XB-GENE-978019]8364OMA, EggNOG
Zebrafish559447scn1labsodium channel, voltage-gated, type I like, alpha b7955ZDB-GENE-060906-1Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    calcium channel    /    Sodium channel protein type 1 subunit alpha
protein    /    transporter    /    voltage-gated sodium channel    /    Sodium channel protein type 1 subunit alpha
protein    /    transporter    /    voltage-gated calcium channel    /    Sodium channel protein type 1 subunit alpha
protein    /    transporter    /    sodium channel    /    Sodium channel protein type 1 subunit alpha
protein    /    transporter    /    voltage-gated ion channel    /    Sodium channel protein type 1 subunit alpha
DTO Classes
protein    /    Ion channel    /    Sodium channel family    /    Nav1.1/SCN1A subfamily    /    Sodium channel protein type 1 subunit alpha

Associated Recombinant Proteins

名前Specification and purityExpression systemProtein label在庫あり詳細を表示

Associated Antibodies

名前SpecificationsSpecies reactivity適用＃テキヨウ＃在庫あり詳細を表示

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      名前Direct Associated TargetsDisease TypeMondoid

      Bibliography

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