TCS 359 - Moligand™, 10mM in DMSO , Inhibitor of fms related receptor tyrosine kinase 3, CAS No.301305-73-7, Inhibitor of fms related receptor tyrosine kinase 3

CAS: 301305-73-7 Cat. No.: T408702 分子式: C₁₈H₂0N₂O₄S 分子量: 360.43 EC番号: 636-890-8 PubChem CID: 1048845

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

Benzo[b]thiophene-3-carboxamide, 2-[(3,4-dimethoxybenzoyl)amino]-4,5,6,7-tetrahydro-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Information

TCS 359 TCS 359 is a potent FLT3 inhibitor with IC50 of 42 nM.
In vitro

TCS 359, a 2-acylaminothiophene-3-carboxamide, is a potent inhibitor of FLT3 with IC50 of 42 nM. TCS 359 inhibits MV4-11 proliferation with IC50 of 340 nM. TCS 359 is highly selective for FLT3 against a panel of kinases.

In vivo

Cell Data

cell lines：

Concentrations：~5 μM

Incubation Time：72 hours

Powder Purity:≥99%

Specifications

同義語

Benzo[b]thiophene-3-carboxamide, 2-[(3,4-dimethoxybenzoyl)amino]-4,5,6,7-tetrahydro-

仕様と純度

Moligand™, 10mM in DMSO

生化学的・生理学的メカニズム

TCS 359 is a potent FLT3 inhibitor with IC50 of 42 nM.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

INHIBITOR

作用メカニズム

Inhibitor of fms related receptor tyrosine kinase 3

名前と識別子

• 異性体SMILES: COC1=C(C=C(C=C1)C(=O)NC2=C(C3=C(S2)CCCC3)C(=O)N)OC
• WGKドイツ: 3
• PubChem CID: 1048845
• 分子量: 360.43

関連ターゲット（人間）

FLT3 Tclin Receptor-type tyrosine-protein kinase FLT3 (1 Activities)

Discover Target: FLT3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

よくある質問

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 301305-73-7, the molecular formula is C18H20N2O4S, and the molecular weight is 360.43 g/mol.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.