Tempol - 10mM in DMSO , CAS No.2226-96-2

CAS: 2226-96-2 Cat. No.: T407895 分子式: C₉H₁₈NO₂ 分子量: 172.24 Beilstein Registry Number: 1422990 EC番号: 218-760-9

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Information

Tempol (4-Hydroxy-TEMPO) is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects. Phase 2.
In vitro

Tempol (4-Hydroxy-TEMPO) is a stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap. Tempol Exhibits radio-protective and anti-proliferative properties. Tempol inhibits oxygen-dependent radiation-induced damage. ^[1] Tempol induces oxidative stress and enhances the levels of p21WAF1 in HL-60 cells in a dose-dependent manner. ^[2]

In vivo

Tempol reduces oxidant stress-mediated renal dysfunction and injury in the rat. ^[3] Tempol prevents cerebral vessel remodeling in hypertensive rats. ^[4] Tempol lowers blood pressure and sympathetic nerve activity but not vascular O2- in DOCA-salt rats. ^[5] Tempol restores mitochondrial and cardiac functions in TNFα-induced oxidative stress and reduces cardiac hypertrophy in chronic hypoxic rats. ^[6]
Cell Data

cell lines：

Concentrations：', 'Concentrations': '

0.05–1.6 mM

Incubation Time：

Powder Purity:

Specifications

仕様と純度

10mM in DMSO

生化学的・生理学的メカニズム

Membrane permeable superoxide scavenger. SOD simulation. Reduce inflammation caused by superoxide anions and peroxynitrite. Reduce oxidative stress.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

名前と識別子

異性体SMILES

CC1(CC(CC(N1[O])(C)C)O)C

WGKドイツ

1

RTECS

TN8991000

分子量

172.24

Beilstein

1422990

Reaxy-Rn

11328213

化学的性質と物理的性質

• 引火点（°F）: 294.80℉
• 引火点（°C）: 146℃
• 融点（°C）: 69-71°C

よくある質問

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2226-96-2, the molecular formula is C9H18NO2, and the molecular weight is 172.24 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.