TH023 , CAS No.T1435096

CAS: T1435096 Cat. No.: T1435096 分子式: C22H21ClF2N4O 分子量: 430.88
注文可能
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Size
USA
ドイツ (EU)*
Price
Qty
1mg
T1435096-1mg
受注生産 · 8~12週間
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Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

概要

TH023 is an inhibitor for the TLR4 signaling pathway, that targets especially the formation of TLR4 homodimer. TH023 inhibits secreted embryonic alkaline phosphatase in cell HEK-Blue hTLR4 with an IC 50 of 0.354 μM, and inhibits the NO expression in RAW264.7 with an IC 50 of 1.61μM. TH023 also inhibits the activation of NF-κB , reduces the nuclear translocation of NF-κB p65. TH023 exhibits anti-inflammatory efficacy in LPS -induced mouse acute sepsis model, and ameliorates the mouse lung injury.

Specifications

保管条件
Store at -20°C
入荷
Ice chest + Ice pads
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
名前と識別子
分子量 430.88

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

証明書(CoA、COO、BSE/TSEと分析図)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
ソリューション計算機
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よくある質問

How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is T1435096, the molecular formula is C22H21ClF2N4O, and the molecular weight is 430.88 g/mol.

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