Tilmicosin - 10mM in DMSO , CAS No.108050-54-0

CAS: 108050-54-0 Cat. No.: T408227 分子式: C₄₆H₈₀N₂O₁₃ 分子量: 869.13 EC番号: 639-676-2 PubChem CID: 5282521

GRADE & PURITY 10mM in DMSO

Synonyms

EL 870 | Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Information

Tilmicosin (EL 870) is a macrolide antibiotic.
In vitro

Tilmicosin inhibits growth of Pasteurella multocida, Pasteurella haemolytica, Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, Streptococcus suis, Actinomyces pyogenes and certain other bacteria at levels of 6.25 μg/mL or less. In general, the MICs for Gram-negative enteric bacteria have been greater than 50 μg/mL. Tilmicosin causes decreases in cardiac SOD and GPX activities.

In vivo

After a subcutaneous injection, tilmicosin is eliminated more slowly from serum and milk, with t1/2 beta S of 29.3 and 41.4 hours, respectively. The apparent volume of distribution of tilmicosin is more than 1 L/kg. The peak serum tilmicosin concentration is 1.56 μg/mL. 6.39 hours after a subcutaneous injection of 10 mg/kg. Tilmicosin is extensively secreted into milk, reaching a maximum concentration of 11.6 μg/mL and having a large AUCmilk/AUCserum ratio of approximately 12:1. Tilmicosin is detectable in milk for 11 days after a single subcutaneous dose.
Cell Data

cell lines：YAPC-PD cells or Panc-1 cells

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

同義語

EL 870 | Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]-

仕様と純度

10mM in DMSO

生化学的・生理学的メカニズム

Tilmicosin (EL 870) is a macrolide antibiotic.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

名前と識別子

異性体SMILES

CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O)N(C)C)O)CCN3C[C@@H](C[C@@H](C3)C)C)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC

PubChem CID

5282521

分子量

869.13

よくある質問

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 108050-54-0, the molecular formula is C46H80N2O13, and the molecular weight is 869.13 g/mol.