trans-Pralsetinib - 10mM in DMSO , Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET inhibitor, CAS No.2097132-93-7, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET inhibitor

CAS: 2097132-93-7 Cat. No.: T656704 分子式: C₂₇H₃₂FN₉O₂ 分子量: 533.60 EC番号: 861-037-3 PubChem CID: 129073603

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

trans-Pralsetinib (trans-BLU-667) is a rearranged during transfection (RET) inhibitor extracted from patent US20170121312A1, Compound Example 129

IC50& Target:RET

Specifications

仕様と純度

10mM in DMSO

生化学的・生理学的メカニズム

trans-Pralsetinib (trans-BLU-667) is a rearranged during transfection (RET) inhibitor extracted from patent US20170121312A1, Compound Example 129.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

INHIBITOR

作用メカニズム

Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET inhibitor

製品の性質

• ALogP: 3.1

名前と識別子

• 異性体SMILES: CC1=CC(=NN1)NC2=NC(=NC(=C2)C)C3CCC(CC3)(C(=O)N[C@@H](C)C4=CN=C(C=C4)N5C=C(C=N5)F)OC
• 代替CAS番号: 2097132-94-8
• PubChem CID: 129073603
• MeSH用語: BLU-667;Cyclohexanecarboxamide, N-((1S)-1-(6-(4-fluoro-1H-pyrazol-1-yl)-3-pyridinyl)ethyl)-1-methoxy-4-(4-methyl-6-((5-methyl-1H-pyrazol-3-yl)amino)-2-pyrimidinyl)-, trans-;gavreto;pralsetinib;trans-N-((1S)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)-3-pyridinyl)ethy
• 分子量: 533.60

関連ターゲット（人間）

RET Tclin Proto-oncogene tyrosine-protein kinase receptor Ret (0 Activities)

Discover Target: RET

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KDR Tclin Vascular endothelial growth factor receptor 2 (0 Activities)

Discover Target: KDR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

よくある質問

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2097132-93-7, the molecular formula is C27H32FN9O2, and the molecular weight is 533.60 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.