Determine the necessary mass, volume, or concentration for preparing a solution.
UCB-5307 - ≥97% , CAS No.1515887-44-1
注文可能
GRADE & PURITY ≥97%
Storage
Store at 2-8°C,Protected from light,Desiccated
Shipped In
Wet ice
Why this grade
≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at 2-8°C,Protected from light,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
概要
UCB-5307 is a potent TNF signaling inhibitor with a K D of 9 nM for human TNFα. UCB-5307 can penetrate the preformed hTNF/hTNFR1 complex.
In Vitro
UCB-5307 inhibits wild-type TNF but does not inhibit L57F TNF. The T 1/2 of UCB-5307 is 3.3 h. UCB-5307 disrupts a preformed hTNF/hTNFR1 complex, can penetrate the preformed complex, dislodging one of the receptors. Preloading hTNF with UCB-5307 blocks one receptor from binding. UCB-5307 binds to a pocket in the centre of the TNF trimer formed by the movement of the TNF monomers, stabilising the distorted trimer, which leads to reduced signalling through TNFR1. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
Specifications
仕様と純度
≥97%
生化学的・生理学的メカニズム
UCB-5307 is a potent TNF signaling inhibitor with a K D of 9 nM for human TNFα. UCB-5307 can penetrate the preformed hTNF/hTNFR1 complex.
保管条件
Store at 2-8°C,Protected from light,Desiccated
入荷
Wet ice
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
純度
≥97%
名前と識別子
| カノニカル・スマイル | OC(C1=NC2=C(N1CC3=CC(C)=CC=C3C)C=CC=C2)C4=CC=NC=C4 |
|---|---|
| 分子量 | 343.42 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
証明書（CoA、COO、BSE/TSEと分析図）
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
化学的性質と物理的性質
| 溶解度 | DMSO : 50 mg/mL (145.59 mM; Need ultrasonic) |
|---|
ソリューション計算機
レビュー
顧客レビュー
よくある質問
What is the purity of this product?
This product is supplied at ≥97% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at 2–8 °C, protected from light, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.
How is this product shipped?
This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 1515887-44-1, the molecular formula is C22H21N3O, and the molecular weight is 343.42 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
Remind me later
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.