URB 937 - モリガンド™, ≥98 , Inhibitor of Fatty acid amide hydrolase, CAS No.1357160-72-5, Inhibitor of Fatty acid amide hydrolase

CAS: 1357160-72-5 Cat. No.: U351248 分子式: C₂₀H₂₂N₂O₄ 分子量: 354.4 EC番号: 802-936-2 PubChem CID: 53394762

GRADE & PURITY Moligand™, ≥98%

Synonyms

cyclohexylcarbamic acid 3'-carbamoyl-6-hydroxybiphenyl-3-yl ester | DTXSID801018151 | BDBM50437227 | MS-25529 | [3-(3-carbamoylphenyl)-4-hydroxyphenyl] N-cyclohexylcarbamate | 3'-(Aminocarbonyl)-6-hydroxy[1,1'-biphenyl]-3-yl N-cyclohexylcarbamate | AC-365

Storage

20℃で保存

Shipped In

アイスチェスト＋アイスパッド

概要

製品概要

URB937は経口活性で末梢に限局したFAAH阻害剤（IC50=26.8 nM）であり、アナンダミド濃度を上昇させる。URB937は脳内のFAAH活性に影響を与えない（血液脳関門を通過しない）。

Specifications

同義語

cyclohexylcarbamic acid 3'-carbamoyl-6-hydroxybiphenyl-3-yl ester | DTXSID801018151 | BDBM50437227 | MS-25529 | [3-(3-carbamoylphenyl)-4-hydroxyphenyl] N-cyclohexylcarbamate | 3'-(Aminocarbonyl)-6-hydroxy[1,1'-biphenyl]-3-yl N-cyclohexylcarbamate | AC-365

仕様と純度

モリガンド™, ≥98

保管条件

20℃で保存

入荷

アイスチェスト＋アイスパッド

等級

Moligand™

アクションタイプ

INHIBITOR

作用メカニズム

Inhibitor of Fatty acid amide hydrolase

純度

≥98%

名前と識別子

• パブケム・シド: 504771192
• パブケム・シド・ウル: https://pubchem.ncbi.nlm.nih.gov/substance/504771192
• カノニカル・スマイル: C1CCC(CC1)NC(=O)OC2=CC(=C(C=C2)O)C3=CC(=CC=C3)C(=O)N
• IUPAC Name: [3-(3-carbamoylphenyl)-4-hydroxyphenyl] N-cyclohexylcarbamate
• InChIKey: CMEQHOXCIGFZNJ-UHFFFAOYSA-N
• INCHI: 1S/C20H22N2O4/c21-19(24)14-6-4-5-13(11-14)17-12-16(9-10-18(17)23)26-20(25)22-15-7-2-1-3-8-15/h4-6,9-12,15,23H,1-3,7-8H2,(H2,21,24)(H,22,25)
• 異性体SMILES: C1CCC(CC1)NC(=O)OC2=CC(=C(C=C2)O)C3=CC(=CC=C3)C(=O)N
• WGKドイツ: 3
• PubChem CID: 53394762
• 分子量: 354.4

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • 分類 Benzene and substituted derivatives
      • Subclass Biphenyls and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• 分類: Benzene and substituted derivatives
• Subclass: Biphenyls and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Biphenyls and derivatives
• Alternative Parents: Benzamides Phenoxy compounds Benzoyl derivatives 1-hydroxy-2-unsubstituted benzenoids Carbamate esters Primary carboxylic acid amides Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Biphenyl - Benzamide - Benzoic acid or derivatives - Phenoxy compound - Benzoyl - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Carbamic acid ester - Primary carboxylic acid amide - Carboxamide group - Carboxylic acid derivative - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Aromatic homomonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as biphenyls and derivatives. These are organic compounds containing to benzene rings linked together by a C-C bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

関連ターゲット（人間）

FAAH Tchem Fatty-acid amide hydrolase 1 (0 Activities)

Discover Target: FAAH

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

関連ターゲット（非人間）

Faah Anandamide amidohydrolase (3907 Activities)

Discover Target: Faah

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用メカニズム

化学的性質と物理的性質

• 分子量: 354.400 g/mol
• XLogP3: 3.500
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 354.158 Da
• Monoisotopic Mass: 354.158 Da
• Topological Polar Surface Area: 102.000 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 492.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

よくある質問

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1357160-72-5, the molecular formula is C20H22N2O4, and the molecular weight is 354.4 g/mol. InChIKey CMEQHOXCIGFZNJ-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.