EnzymoPure™, ≥2 units/mg dry weight EnzymoPure™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 15 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Uricase from Candida yeast has a molecular weight of ~120,000 daltons and an optimum pH of 8.5. The enzyme is stable at pH 8.5-9.5 and at temperatures below 35°C. The pI is 5.6. It is inhibited by various purine analogs of urate, and by copper chelating agents. The enzyme is highly specific for uric acid. Mice deficient in uricase develop uric acid nephropathy and diabetes insipidus which can be mitigated with recombinant uricase treatment.
Oxidizes uric acid
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
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View spec sheet →Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 D2502559 | Certificate of Analysis | Mar 18, 2025 | U128546 |
| D2429469 | Certificate of Analysis | Mar 14, 2024 | U128546 |
| D2429470 | Certificate of Analysis | Mar 14, 2024 | U128546 |
| I2305219 | Certificate of Analysis | Aug 15, 2023 | U128546 |
| D2230082 | Certificate of Analysis | Mar 03, 2022 | U128546 |
| 1. Zheng Xinyu, Yang Yang, Gao Feng, Li Huihui, Yang Weikang, Guo Dong-Yu, Chen Shengming, Pan Qinhe. (2022) Enzyme-free fluorescence determination of uric acid by combining CdTe quantum dots with metal–organic framework for signal amplification. MICROCHIMICA ACTA, 189 (11): (1-9). [PMID:36318325] [10.1007/s00604-022-05535-8] |
| 2. Fuad Abduro Bushira, Shimeles Addisu Kitte, Yong Wang, Haijuan Li, Ping Wang, Yongdong Jin. (2021) Plasmon-Boosted Cu-Doped TiO2 Oxygen Vacancy-Rich Luminol Electrochemiluminescence for Highly Sensitive Detection of Alkaline Phosphatase. ANALYTICAL CHEMISTRY, [PMID:34743510] [10.1021/acs.analchem.1c03842] |
| 3. Guojun Cao, Can Wu, Yong Tang, Chidan Wan. (2019) Ultrasmall HKUST-1 nanoparticles decorated graphite nanosheets for highly sensitive electrochemical sensing of DNA damage biomarker 8-hydroxy-2’-deoxyguanosine. ANALYTICA CHIMICA ACTA, [PMID:30851856] [10.1016/j.aca.2019.01.031] |
| 4. Aijin Fang, Qiongqiong Wu, Qiujun Lu, Hongyu Chen, Haitao Li, Meiling Liu, Youyu Zhang, Shouzhuo Yao. (2016) Upconversion ratiometric fluorescence and colorimetric dual-readout assay for uric acid. BIOSENSORS & BIOELECTRONICS, [PMID:27471157] [10.1016/j.bios.2016.07.055] |
| 5. Yuanting Xie, Kaidi Li, Jing Liu, Ying Zhou, Chuangjie Zhang, Yan Yu, Jianlong Wang, Lei Su, Xueji Zhang. (2024) A smart lab on a wearable microneedle patch with convolutional neural network-enhanced colorimetry for early warning of syndrome of inappropriate antidiuretic hormone secretion. Aggregate, [PMID:] [10.1002/agt2.671] |
| 6. Zehua Guo, Yiren Cao, Liuyin Fan, Weiwen Liu, Li Wei, Yixin Ma, Jicun Ren, Qiang Zhang, Chengxi Cao. (2024) A temperature-independent model of dual calibration standards for onsite and point-of-care quantification analyses via electrophoresis titration chip. ANALYTICA CHIMICA ACTA, [PMID:38245206] [10.1016/j.aca.2024.342207] |
| 7. Yanshu Xiang, Yongjie Zhao, Yifan Jiang, Jiarui Feng, Xiaoyi Zhang, Wei Su, Yingjie Zhou, Peng Wei, Sze Shin Low, Hao Nan Li. (2024) Battery-Free and Multifunctional Microfluidic Janus Wound Dressing with Biofluid Management, Multi-Indicator Monitoring, and Antibacterial Properties. ACS Applied Materials & Interfaces, [PMID:39264683] [10.1021/acsami.4c09891] |
| 8. Yunfeng Bai, Xiaoxuan Fan, Guoning Chen, Zhilong Zhao. (2024) Efficient and fast detection of uric acid based on a colorimetric sensing method. Analytical Methods, [PMID:39157953] [10.1039/D4AY01053A] |
| 9. Yi-Kun Wang, Ya-Jun Chen, Yao Pan, Yu Hai-Yin. (2024) Prussian Blue and Polyvinylpyrrolidone-Embedded Hollow Fiber Gradient Polysulfone Membrane for Uric Acid Biosensor Application. JOURNAL OF APPLIED POLYMER SCIENCE, [PMID:] [10.1002/app.56649] |
| 10. Chenlong He, Huawei Liu, Ming Yin, Jing Chen, Wensi Huang, Han Zhou, Shengming Wu, Yilong Wang. (2025) UOx@HMnO2 Biozyme-Nanozyme Driven Electrochemical Platform for Specific Uric Acid Bioassays. ANALYST, [PMID:40035522] [10.1039/D4AN01512F] |
| 11. Ziting Bao, Sheng Lu, Duo Zhang, Guanyu Wang, Xiaolin Cui, Guozhen Liu. (2024) Wearable Microneedle Patch for Colorimetric Detection of Multiple Signature Biomarkers in vivo Toward Diabetic Diagnosis. Advanced Healthcare Materials, [PMID:38353398] [10.1002/adhm.202303511] |
| 12. Fangbing Wang, Jing Ren, Qiwen Peng, Hongyi Sun, Qiankun Zeng, Yongheng Zhang, Guoyue Shi, Min Zhang. (2024) Janus Separation-Sensing Membrane Hosted with Enzyme@MOF Nanoreactor for Real-Time Blood Sensing. ANALYTICAL CHEMISTRY, [PMID:39264829] [10.1021/acs.analchem.4c03285] |
| 13. Chunjiao Qi, Jintao Chen, Yuhui Shang, Yu Yang, Kangyan Wang, Jinyang Chen. (2024) Target-Triggered Ultrafast Chondroitin Gelation Enabled Power-Free and Point-of-Care Bioassays. ANALYTICAL CHEMISTRY, [PMID:39436985] [10.1021/acs.analchem.4c04130] |
| 14. Xiwang Hou, Tianhao Chen, Chunyan Wang, Fanyu Liu, Minggang Zhao, Ye Ma. (2025) Analyte mediated transformation of metasurface: A dual-mode plasmonic sensing platform for uric acid. TALANTA, [PMID:41166825] [10.1016/j.talanta.2025.129024] |
| 15. Ruoxuan Jiang, Lei Pan, Fan Yang, Shudong Zhang, Dan Lin, Changlong Jiang. (2025) MOF-on-MOF multi-enzyme cascade sensor for visual monitoring of uric acid in body fluids. TALANTA, [PMID:41240652] [10.1016/j.talanta.2025.129115] |
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