Verteporfin - Moligand™, ≥97% , CAS No.129497-78-5

CAS: 129497-78-5 Cat. No.: V129759 分子式: C₄₁H₄₂N₄O₈ 分子量: 718.79 EC番号: 893-418-5

GRADE & PURITY Moligand™, ≥97%

Synonyms

Visudyne | BPD-MA | CL 318952

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

概要

Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis[1]. Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation.

Specifications

同義語

Visudyne | BPD-MA | CL 318952

仕様と純度

Moligand™, ≥97%

生化学的・生理学的メカニズム

Vitepofin is a photosensitizer for photodynamic therapy, which can be used to eliminate abnormal blood vessels in eyes related to macular degeneration and other diseases. Vitipofen can accumulate in abnormal blood vessels. When stimulated by non-thermal r

保管条件

Protected from light,Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

注

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

純度

≥97%

名前と識別子

パブケム・シド

488195426

パブケム・シド・ウル

https://pubchem.ncbi.nlm.nih.gov/substance/488195426

異性体SMILES

CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5[C@@]6([C@@H](C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)OC)C(=C3C)CCC(=O)O)C=C

WGKドイツ

3

分子量

718.79

Reaxy-Rn

14615024

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14615024&ln=

化学的性質と物理的性質

• 溶解度: DMSO 100 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
• 感度: Light sensitive
• 分子量: 718.800 g/mol
• XLogP3: 4.900
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 12
• Exact Mass: 718.3 Da
• Monoisotopic Mass: 718.3 Da
• Topological Polar Surface Area: 174.000 Ų
• Heavy Atom Count: 53
• Formal Charge: 0
• Complexity: 1500.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1