Z-DEVD-AFC - BioReagent, ≥98% , CAS No.1135416-11-3

CAS: 1135416-11-3 Cat. No.: Z647630 分子式: C₃₈H₃₀F₃N₅O₁₄ 分子量: 821.7

GRADE & PURITY BioReagent, ≥98%

Synonyms

Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-AFC | Caspase-3 Substrate IV, Fluorogenic

Storage

Protected from light,Store at -20°C,Desiccated,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Application

Apoptosis, Cell signaling, Drug screening, Enzyme activity assay

概要

Z-DEVD-AFC is a synthetic polypeptide whose core part consists of four amino acids: Asp-Glu-Val-Asp (DEVD), linked to a fluorophore AFC (7-amino-4-trifluoromethylcoumarin). During the process of cell apoptosis, especially when some caspases are activated, Z-DEVD-AFC will be cleaved to release AFC, which emits bright fluorescence and acts as a real-time monitor of the apoptotic process.

Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity.

Specifications

同義語

Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-AFC | Caspase-3 Substrate IV, Fluorogenic

仕様と純度

BioReagent, ≥98%

生化学的・生理学的メカニズム

Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity.

安定性と保管

Store at -20℃ long term (24 months).  Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle. Store in the dark. Desiccated.

保管条件

Protected from light,Store at -20°C,Desiccated,Avoid repeated freezing and thawing

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

BioReagent

純度

≥98%

名前と識別子

代替CAS番号

1177935-21-5

分子量

821.7

化学的性質と物理的性質

• 溶解度: Soluble in 30% ACN/H2O.