1,3-Propanediol - analytical standard , CAS No.504-63-2

CAS: 504-63-2 Cat. No.: P108207 Molecular Weight: 76.09 Beilstein Registry Number: 969155 EC Number: 207-997-3
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GRADE & PURITY Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
Synonyms
2-Deoxyglycerol | HSDB 8263 | J-503943 | CAS-504-63-2 | DTXCID6021246 | 1,3-PROPANEDIOL | 1,3-propane-diol | propan-1,3-diol | (HOCH2)2CH2 | CHEBI:16109 | InChI=1/C3H8O2/c4-2-1-3-5/h4-5H,1-3H | 1,3-PROPANDIOL | propane 1.3-diol | 1.3-propanediol | C02457
Storage
Desiccated,Room temperature
Shipped In
Normal
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Size
Status
Price
Qty
250mg
P108207-250mg
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Why this grade

analytical standard Analytical standard for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Desiccated,Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 171 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
2-Deoxyglycerol | HSDB 8263 | J-503943 | CAS-504-63-2 | DTXCID6021246 | 1, 3-PROPANEDIOL | 1, 3-propane-diol | propan-1, 3-diol | (HOCH2)2CH2 | CHEBI:16109 | InChI=1/C3H8O2/c4-2-1-3-5/h4-5H, 1-3H | 1, 3-PROPANDIOL | propane 1.3-diol | 1.3-propanediol | C02457
Specifications & Purity
analytical standard
Storage
Desiccated, Room temperature
Shipped In
Normal
Grade
Analytical standard
Names and Identifiers
Canonical SmilesC(CO)CO
IUPAC Namepropane-1,3-diol
InChIKeyYPFDHNVEDLHUCE-UHFFFAOYSA-N
INCHI1S/C3H8O2/c4-2-1-3-5/h4-5H,1-3H2
Isomeric SMILES C(CO)CO
WGK Germany 1
RTECS TY2010000
Molecular Weight 76.09
Beilstein 969155
Reaxy-Rn 969155
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=969155&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic oxygen compounds
ClassOrganooxygen compounds
SubclassAlcohols and polyols
Intermediate Tree Nodes Not available
Direct ParentPrimary alcohols
Alternative Parents Hydrocarbon derivatives  
Molecular FrameworkAliphatic acyclic compounds
Substituents Hydrocarbon derivative - Primary alcohol - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as primary alcohols. These are compounds comprising the primary alcohol functional group, with the general structure RCOH (R=alkyl, aryl).
External Descriptors a small molecule
3D Structure
Interactive Chemical Structure Model





Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
B2628172Certificate of AnalysisMar 13, 2026 P108207
F2520041Certificate of AnalysisJun 30, 2025 P108207
C2421049Certificate of AnalysisMar 28, 2024 P108207
J2231142Certificate of AnalysisNov 24, 2022 P108207
J2027170Certificate of AnalysisAug 08, 2022 P108207
Chemical and Physical Properties
Refractive Index1.44
Flash Point(°F)165 °F
Flash Point(°C)74 °C
Boil Point(°C)214°C
Melt Point(°C)-27°C
Molecular Weight76.090 g/mol
XLogP3-1.000
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass76.0524 Da
Monoisotopic Mass76.0524 Da
Topological Polar Surface Area40.500 Ų
Heavy Atom Count5
Formal Charge0
Complexity12.400
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Bio-based Chemicals: From Platform Molecules to Application Scenarios — Trend Insights and Aladdin’s Product Portfolio
A Practical Guide to Fragrance Compositions: Turning a Black-Box Formula into an Engineerable System—Compatibility, Stability, Controlled Release, Traceability, and Selection
Experimental Evaluation of Triphosgene in Organic Synthesis: Understanding Its Selection Logic Through Reaction Tasks
Understanding Polyester Resins for Coatings: Structure Design, Key Indicators, and Coating Film Performance
Failure Mechanisms, Application Limitations, and Systematic Improvement Directions for Polyester Coatings
Solvents, Co-solvents, and Solubilization Systems in Home and Personal Care Formulations: Classification, Functions, and Selection Guide
Why Do Alcohols Differ in Function: Why Is Glycerol Mainly Moisturizing, Propylene Glycol Mainly Solubilizing, and Isopropyl Alcohol Fast-Drying? — Understanding Personal Care Formulation Functions from Structural Differences
Thickening, Suspension, Auxiliary Stabilization, and Agglomeration Mechanisms of Xanthan Gum in Personal Care Formulations: From Molecular Structure to Processing Applications
Why Limonene Can Soften Greasy Soils Yet Is Difficult to Dissolve in Water: Understanding the Cleaning Mechanism and Formulation Applications of Naturally Derived Solvents from Molecular Structure
What Is Synthetic Biology? The Industrialization Pathway from Upstream Reagent Toolchains to Biomanufacturing Applications
Analysis of Structural Differences in Diols: Moisturization, Co-solvency, Skin Feel, and Formulation Selection for Propylene Glycol, Butylene Glycol, and Medium- to Long-Chain 1,2-Alkanediols
Citations of This Product
References
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130. Lusheng Huang, Xu Zhou, Nasha Wu, Yaqin Sun, Zhilong Xiu.  (2024)  Selective extraction of 1,3-propanediol by phenylboronic acid-based ternary extraction system.  JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY,      [PMID:] [10.1002/jctb.7647]
131. Ruili Ma, Weiguo Wu, Yikang Shu, Ran Gao, Ziyu Wang, Daoquan Tang, Yan Du, Shuai Ji.  (2025)  Simultaneous extraction and in situ separation of flavonoids and alkaloids from mulberry leaves using a pH-responsive deep eutectic solvent/water system.  FOOD CHEMISTRY,      [PMID:39884234] [10.1016/j.foodchem.2025.143008]
132. Wei Ma, Yanxia Liu, Xiaoli Jiang, Lin Zhao, Yagang Zhang, Panfeng Zhao, Yen Wei.  (2024)  Solvation enabled highly efficient gradient assembly creates robust metal–phenolic coatings.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:39742745] [10.1016/j.jcis.2024.12.193]
133. Huang Zhichao, Wang Lin, Wu Hongfu, Zhang Junfeng, Wang Zhuo, Sun Fu, Duan Huimin, Qi Dongming.  (2024)  Study on the flame retardancy of reactive PU modified in situ using ammonium polyphosphate.  Journal of Coatings Technology and Research,      [PMID:] [10.1007/s11998-024-00968-7]
134. Xiaoshuai Yu, Mo Zhang, Lingjie Dai, Shah Noor, Yan Liu, Chuncheng Yang, Jianshe Lian, Guoyong Wang.  (2025)  Surveying of electrocatalytic performance on water splitting to metal stoichiometry in iron-cobalt and nickel ternary transition metal phosphides.  JOURNAL OF POWER SOURCES,      [PMID:] [10.1016/j.jpowsour.2024.236148]
135. Zhangcheng Gao, Lianfang Feng, Xueping Gu, Jintang Duan, Mingzhe Jiang, Cailiang Zhang.  (2024)  Synthesis and characterization of linear hybrid aliphatic/aromatic copolyurea via one-step feeding method.  JOURNAL OF APPLIED POLYMER SCIENCE,      [PMID:] [10.1002/app.56189]
136. Hao Yuan, Hanxiang Guo, Zhaosheng Huang, Ping Zhang, Zhe Wang, Chunde Jin.  (2025)  Synthesis of multifunctional polyurethane wood coating from epoxidized soybean oil and CO2-based polyol.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2025.136162]
137. Chenxin Zhou, Yiting Liu, Bo Ouyang, Sen Lin, Yonghua Wang.  (2024)  Systematic evaluation of polyol-assisted acidic deep eutectic solvent pretreatment for improving enzymatic hydrolysis of wheat straw.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2024.118219]
138. De Bai, Zhenyuan Wang, Yuan Xiao, Tianqi Liu, Yan Pu, Huaiqing Sun, Mi Wang, Chaowan Guo, Jiaheng Zhang.  (2024)  Transdermal delivery of elastin peptide assisted by betaine-based deep eutectic solvent to ameliorate skin photoaging.  Biomaterials Advances,      [PMID:39053386] [10.1016/j.bioadv.2024.213965]
139. Ke Yan, Xianglin Liu, Lin Li, Shuyu Zhu, Lijuan Zheng, Shuyang He, Xiaomin Jia, Wuzi Dong, Yupeng Liu, Zhoumin Lu, Fangxia Yang.  (2024)  Ultrasound-assisted deep eutectic solvents extraction of polysaccharides from Loquat leaf: Process optimization and bioactivity study.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:38908619] [10.1016/j.ijbiomac.2024.133308]
140. Jing Fan, Xin Zhang, Nan He, Fenhong Song, Xu Wang.  (2025)  Investigation on novel deep eutectic solvents with high carbon dioxide adsorption performance.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2025.117870]
141. Xin Jin, Ang Li, Zhaoyuan Dai, Yi Li, Xinchi Feng, Feng Qiu.  (2025)  Resina Draconis Promotes Diabetic Wound Healing by Regulating the AGE-RAGE Pathway to Modulate Macrophage Polarization.  CURRENT ISSUES IN MOLECULAR BIOLOGY,  47  (9): (748).  [PMID:41020870] [10.3390/cimb47090748]
142. Fenghua Liu, Yunjiao Gu, Yigu Hu, Zan Wang, Yuesheng Ning, Robert Bradley, Deyuan Lou, Binyuan Zhao, Weiping Wu.  (2022)  Freestanding Ultrathin Precisely Structured Hierarchical Porous Carbon Blackbody Film for Efficient Solar Interfacial Evaporation.  Solar RRL,  (2): (2200803).  [PMID:] [10.1002/solr.202200803]
143. Ning Yan, Lei Ding, Tong Wu, Sihang Zhang, Feng Yang, Ya Cao, Ming Xiang.  (2021)  Shutdown-Functionalized Poly Ethylene-Vinyl Alcohol Sulfonate Lithium and Poly (Vinyl Alcohol) Composite Lithium-Ion Battery Separator.  JOURNAL OF THE ELECTROCHEMICAL SOCIETY,  168  (11): (110510).  [PMID:] [10.1149/1945-7111/ac330c]
144. Yan Zhang, Xiaowei Chen, Wei Li, Baoyi Wang, Qian Zhang, Zhuo Zhao, Yafei Wang, Ying Guan, Yongjun Zhang.  (2025)  Construction of Stretchable, Tough and Damped Eutectogel Resistant to −100 °C using 2-Methyl-1,3-Propanediol Based Deep Eutectic Solvent.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202511554]
145. Feipeng Huang, Jiancong Lu, Xinchen Xiang, Yukun Qian, Ge Li, Dan Lu, Guozhong Shi, Lin Zhang.  (2025)  Dual-functional polyethyleneimine engineered interfacial polymerization for ultra-high flux reverse osmosis membranes with moderate salt rejection.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.132926]
146. Longyin Wan, Zhilin Dong, Yun Li, Xin Li, Zhihui Zhao, Xiaoming Li, Weichao Chen.  (2025)  Synthesis of Biobased Poly(propylene 2,5-furandicarboxylate)-block-polycaprolactone for Stretchable Nanofiber Membranes Used in Oil–Water Separation.  ACS Applied Polymer Materials,      [PMID:] [10.1021/acsapm.5c00484]
147. Ning Zisheng, Li Yuhan, Dai Lingmei, Liu Dehua, Du Wei.  (2025)  Advancing the synthesis of trimethylene carbonate: a high-yield green synthesis route.  Bioresources and Bioprocessing,  12  (1): (1-13).  [PMID:40261450] [10.1186/s40643-025-00877-6]
148. Duo Xu, Xinyang Sun, Simiao Wu.  (2025)  Arginine- and lysine-modified forward osmosis membranes with simultaneous enhancement of water flux and antibacterial properties: Performance and mechanisms.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2025.117058]
149. Jiao Li, Shuai Tang, Yonglai Lu, Zhao Wang, Liqun Zhang.  (2025)  Design and Synthesis of Biobased, Biodegradable Polyester for Chewing Gum.  MACROMOLECULAR RAPID COMMUNICATIONS,      [PMID:40320751] [10.1002/marc.202500262]
150. Jianglong Deng, Lintao Chen, Hao Chen, Jiazhuang Guo, Cai-Feng Wang, Su Chen.  (2025)  Green-Emissive Carbon Dots: Microwave Synthesis, Optical Properties, and Fluorescence Mechanism.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.5c01320]
151. Xianfeng Li, Qiaoying Wang, Xingzhong Cao, Jie Zhang, Zhichao Wu, Zhiwei Wang.  (2025)  Boric Acid’s Dual Role in Controlling Interfacial Polymerization for High-Performance Reverse Osmosis Membranes with Enhanced Water Permeability and Contaminant Sieving.  ACS ES&T Engineering,      [PMID:] [10.1021/acsestengg.5c00258]
152. Chengcheng Suo, Xiaochang Zhang, Xinai Li, Jifang Zhang, Hongru Zhang, Rui Teng, Wei Li, Sha Luo, Bing Tian, Qingjiang Pan, Chunhui Ma, Zhijun Chen, Shouxin Liu.  (2025)  Photocatalytic biorefining green closed-loop: Photocatalytic alkali lignin depolymerization in supramolecular solvent.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2025.117642]
153. Fengqin Guo, Jiajun Zhang, Xiang Hui, Yan Cao, Peng He, Huiquan Li, Liguo Wang.  (2025)  Modulating the selective adsorption of biobased diol carbon-oxygen bonds for the synthesis of cyclic carbonates.  APPLIED CATALYSIS A-GENERAL,      [PMID:] [10.1016/j.apcata.2025.120417]
154. Yi Yang, Yuxi Si, Libin Liu, Hairui Lin, Chuan Qin, Dangguo Cheng, Youwei Cheng.  (2025)  Selective Hydrogenation of 5-Hydroxymethylfurfural to 2,5-Bis(hydroxymethyl)furan over Hydroxyl-Enriched Pt/CeO2 Catalysts.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.5c00644]
155. Ruotong Yao, Lijiaqi Zhang, Chao Wang, Min Wu.  (2025)  Highly water- and oil-resistant cellulose paper fabricated through partial dissolution and regeneration based on different coagulation bath.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41075896] [10.1016/j.ijbiomac.2025.148160]
156. Huanhuan Hu, Linyun Luo, Zhongyuan Liu, Lin Tian, Guanjia Zhao.  (2025)  Experimental study and MD simulation of neutral choline–based deep eutectic solvents regulated by ethanol.  FLUID PHASE EQUILIBRIA,      [PMID:] [10.1016/j.fluid.2025.114605]
157. Simeng Wang, Yi Wei, Mengqi Ma, Kaiyu He, Bo Wang.  (2025)  Two-step interfacial polymerization for bilayer polyamide membranes with a gradient-density structure and enhanced desalination performance.  DESALINATION,      [PMID:] [10.1016/j.desal.2025.119585]
158. Lihuang Wu, Tingting Zhao, Junhua Li, Yiyan He, Yuwen Cui, Zhongwei Gu, Hongli Mao.  (2025)  Programmable Biodegradation of Photo-Cross-Linked Poly(trimethylene carbonate) Elastomers via Competitive Thiol–ene Click Chemistry.  BIOMACROMOLECULES,      [PMID:41275392] [10.1021/acs.biomac.5c01667]
159. Zanming Zhu, Faxiang Feng, Jiale Li, Guanhui Wang, Guilin Dong, Runlin Han.  (2025)  Selective solvent resistant polyimide composite membranes with efficient separation performance in antibiotics.  Results in Engineering,      [PMID:] [10.1016/j.rineng.2025.108653]
160. Tianjun Hu, Mengtian Kang, Yaru Chen, Yuzhu Tian, Ying Wang, Jiale Li, Junming Zhang, Ergui Luo, Baoliang Lv, Jianfeng Jia.  (2025)  Pt-Triggered Reversal in Acetone Sensing: Crystal Phase-Dependent Dispersion Governs Performance of Fe2O3.  ACS Sensors,      [PMID:41363812] [10.1021/acssensors.5c02766]
161. Zhiguo Hu, Yuesheng Zhang, Jiangang Zhang, Wen Cao, Xiong Liu, Hongtao Lu, Jianna Bao.  (2026)  Interfacial engineering of polylactic acid via dynamic vulcanization of bio-based polyester toward simultaneous toughening and accelerated crystallization.  POLYMER,      [PMID:] [10.1016/j.polymer.2026.129577]
162. Yushu Tian, Min Wang, Jiadong Wang, Yi Wei, Yixuan Chang, Xuan Qin, Liqun Zhang.  (2026)  Tuning Hard-Segment Regularity for Microphase Control and Property Enhancement in Hydroxyl-Terminated Polybutadiene-Based Polyurethane Elastomers.  MACROMOLECULES,      [PMID:] [10.1021/acs.macromol.5c02654]
163. Kai Wu, Yijie Zheng, Mingfan Li, Wenguang Zheng, Mingguang Song, Liandong Hu, Ke Yang, Jiajun Yu, Huiyan Zhang.  (2026)  Overcoming bamboo recalcitrance via deep eutectic solvent pretreatment combined with pyrolysis for enhanced pyrolytic sugars.  BIOMASS & BIOENERGY,      [PMID:] [10.1016/j.biombioe.2026.108982]
164. Jianquan Peng, Siheng Zhao, Shengchao Zhao, Mingbin Chen, Kuo Chen, Q. Jason Niu.  (2026)  Synthesis of Thin Film Composite Membranes via Acid-Assisted Interfacial Polymerization for Water Desalination.  WATER RESEARCH,      [PMID:41679037] [10.1016/j.watres.2026.125517]
165. Fanghui Cheng, Xicui Zhang, Zhixing Li, Qing Dang, Xuan Ling, Qian Zhang, Zhao Wang, Jie Ai, Xiaoran Hu.  (2026)  In situ and real-time monitoring of the internal temperature, pressure, and current of lithium-ion batteries for long cycle life safety using a flexible multi-parameter sensor array.  Journal of Materials Chemistry A,      [PMID:] [10.1039/D5TA09703G]
166. Zutian Bi, Ying Ge, Zhao Chen, Xiaomei Pei, Zhenggang Cui, Binglei Song.  (2026)  Strong Viscoelastic Glycerol Solutions Formed from Phenylalanine-Based Amine Oxide Surfactants.  Soft Matter,      [PMID:41733984] [10.1039/D5SM01213A]
167. Lifei Chen, Xuetao Yan, Tianliang Li, Kaixuan Cui, Lixing Lin, Zeyu Li, Yingying Chen, Zhenzhen Li, Lingyan Feng.  (2026)  Interpretable Active Learning for Discovering G-Quadruplex Deep-Eutectic Circularly Polarized Luminescence Materials With High Dissymmetry Factor and Quantum Yield.  Aggregate,  (3): (e70307).  [PMID:] [10.1002/agt2.70307]
168. Xin Luo, Xuan Ling, Xian Li, Zhao Wang, Xiaoran Hu.  (2026)  A Stretchable Piezoelectric/pH Bimodal Sensor for Motion and Sweat Monitoring Using Polylactide/Polyester Elastomer/Carbon Quantum Dots Nanofiber.  ACS Applied Polymer Materials,      [PMID:] [10.1021/acsapm.5c04604]
169. Xuetao Yan, Lifei Chen, Yuze Ren, Kaixuan Cui, Tianliang Li, Lixing Lin, Zeyu Li, Haicheng Song, Yingying Chen, Zhenzhen Li, Lingyan Feng.  (2026)  Explainable Machine Learning for Solvents-Driven G-quartet Circularly Polarized Luminescence Material in Multilevel Anti-counterfeiting.  Advanced Optical Materials,      [PMID:] [10.1002/adom.71180]
170. Zhou Xiaorui, Yang Ying, Lv Chang, Cheng Xinru, Hao Wenbo, Su Tingting, Huang Chenhao, Hu Bing.  (2026)  Influence of Carbon Chain Length and Odd–Even Effect on the Properties of Azelaic Acid-Based Aliphatic Polyesters.  JOURNAL OF POLYMERS AND THE ENVIRONMENT,  34  (4): (80).  [PMID:] [10.1007/s10924-026-03770-1]
171. Qian Zhang, Mingyang Cao, Chenxia Tang, Yuqing Zhou, Xiaoli Peng.  (2026)  High-Performance Solid Polymer Electrolyte Constructed from Long-Chain Regulated Random Copolymers and Porous PI Composites.  Polymers,  18  (6):   [PMID:] [10.3390/polym18060685]
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