1-Ethylpiperazine - ≥98% , CAS No.5308-25-8

CAS: 5308-25-8 Cat. No.: E103219 Molecular Weight: 114.19 Beilstein Registry Number: 102971 EC Number: 226-166-6

GRADE & PURITY ≥98%

Synonyms

N-Ethyl piperazine(NEP) | W-105771 | N-ethylpiperizine | P17082 | DTXSID8073346 | 2,2'-Azobis(2-amidinopropane)hydrochloride | AM81362 | EC 226-166-6 | EINECS 226-166-6 | STL168346

Storage

Room temperature,Argon charged

Shipped In

Normal

Overview

1-Ethylpiperazine may be used in the preparation of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride.

Specifications

Synonyms

N-Ethyl piperazine(NEP) | W-105771 | N-ethylpiperizine | P17082 | DTXSID8073346 | 2, 2'-Azobis(2-amidinopropane)hydrochloride | AM81362 | EC 226-166-6 | EINECS 226-166-6 | STL168346

Specifications & Purity

≥98%

Storage

Room temperature, Argon charged

Shipped In

Normal

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 504755353
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504755353
• Canonical Smiles: CCN1CCNCC1
• IUPAC Name: 1-ethylpiperazine
• InChIKey: WGCYRFWNGRMRJA-UHFFFAOYSA-N
• INCHI: 1S/C6H14N2/c1-2-8-5-3-7-4-6-8/h7H,2-6H2,1H3
• Isomeric SMILES: CCN1CCNCC1
• WGK Germany: 1
• RTECS: TM0815500
• UN Number: 1993
• Molecular Weight: 114.19
• Beilstein: 102971
• Reaxy-Rn: 102971
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=102971&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Diazinanes
      • Subclass Piperazines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Diazinanes
• Subclass: Piperazines
• Intermediate Tree Nodes: Not available
• Direct Parent: N-alkylpiperazines
• Alternative Parents: Trialkylamines Dialkylamines Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: N-alkylpiperazine - Tertiary aliphatic amine - Tertiary amine - Azacycle - Secondary amine - Secondary aliphatic amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Amine - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as n-alkylpiperazines. These are organic compounds containing a piperazine ring where the nitrogen ring atom carries an alkyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Miscible with water.
• Sensitivity: Air sensitive.
• Refractive Index: 1.469
• Flash Point(°F): 109.4 °F
• Flash Point(°C): 43°
• Boil Point(°C): 157°C
• Melt Point(°C): -60°C
• Molecular Weight: 114.190 g/mol
• XLogP3: 0.000
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 114.116 Da
• Monoisotopic Mass: 114.116 Da
• Topological Polar Surface Area: 15.300 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 57.500
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

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5. Fengting Li, Wentao Qu, Yunchao Peng, Liqiang Yang, Li Wang, Huiling Su, Miantuo Li, Zhikun Wang, Jingyue Wang, Yu Fu, Songqing Hu.  (2025)  Regulating π-π interactions in carbon dots via N-doping & ionic liquid modification for enhanced efficiency in 1 M HCl.  CORROSION SCIENCE,      [PMID:] [10.1016/j.corsci.2025.112798]

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