DL-Cysteine - Moligand™,≥97% , CAS No.3374-22-9

CAS: 3374-22-9 Cat. No.: C110437 Molecular Weight: 121.16 Beilstein Registry Number: 1721406 EC Number: 222-160-2
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
Synonyms
SR-01000944791 | Tox21_111766_1 | [35s]cysteine | A821916 | CCRIS 8598 | FD21272 | NCGC00248803-03 | SY009625 | d,l-cysteine | CAS-3374-22-9 | Zystein | CAS_5862 | L-Cysteine-13C3 | NSC 63864 | CHEBI:15356 | Hcys | UNII-5CM45Q5YAF | AB02703 | L-CYSTEINE (
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5g
C110437-5g
3

$9.90

$11.90
Save $2.00 (16.81%)
25g
C110437-25g
2

$25.90

$29.90
Save $4.00 (13.38%)
100g
C110437-100g
1

$94.90

$109.90
Save $15.00 (13.65%)
500g
C110437-500g
1

$443.90

$499.90
Save $56.00 (11.20%)
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™,≥97% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 14 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Product Description

Cysteine is a non-essential amino acid that can be synthesized by the human body under normal physiological conditions if a sufficient quantity of methionine is available. Cysteine is commonly used as a precursor in the food and pharmaceutical industries. Cysteine is used as a processing aid for baking, as an additive in cigarettes, as well as in the preparation of meat flavours.

Product Application
NMDA agonist that is an agonist at quisqualate receptors at high concentration.

Specifications

Synonyms
SR-01000944791 | Tox21_111766_1 | [35s]cysteine | A821916 | CCRIS 8598 | FD21272 | NCGC00248803-03 | SY009625 | d, l-cysteine | CAS-3374-22-9 | Zystein | CAS_5862 | L-Cysteine-13C3 | NSC 63864 | CHEBI:15356 | Hcys | UNII-5CM45Q5YAF | AB02703 | L-CYSTEINE (
Specifications & Purity
Moligand™, ≥97%
Biochemical and Physiological Mechanisms
NMDA agonist that is an agonist at quisqualate receptors at high concentration.
Storage
Store at 2-8°C, Argon charged
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Purity
≥97%
Names and Identifiers
Canonical SmilesC(C(C(=O)O)N)S
IUPAC Name2-amino-3-sulfanylpropanoic acid
InChIKeyXUJNEKJLAYXESH-UHFFFAOYSA-N
INCHI1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)
Isomeric SMILES C(C(C(=O)O)N)S
WGK Germany 3
Molecular Weight 121.16
Beilstein 1721406
Reaxy-Rn 1721406
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1721406&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct ParentCysteine and derivatives
Alternative Parents Alpha amino acids  Amino acids  Monocarboxylic acids and derivatives  Carboxylic acids  Alkylthiols  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Cysteine or derivatives - Alpha-amino acid - Amino acid - Alkylthiol - Carboxylic acid - Monocarboxylic acid or derivatives - Organic nitrogen compound - Hydrocarbon derivative - Primary amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic oxide - Primary aliphatic amine - Organopnictogen compound - Carbonyl group - Amine - Organic oxygen compound - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as cysteine and derivatives. These are compounds containing cysteine or a derivative thereof resulting from reaction of cysteine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors sulfur-containing amino acid - alpha-amino acid
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Adam17 ADAM17 (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot NumberCertificate TypeDateItem
C2610598Certificate of AnalysisJan 31, 2026 C110437
C2610599Certificate of AnalysisJan 31, 2026 C110437
C2610600Certificate of AnalysisJan 31, 2026 C110437
H2511032Certificate of AnalysisAug 21, 2025 C110437
K2216362Certificate of AnalysisOct 17, 2022 C110437
K2216363Certificate of AnalysisOct 17, 2022 C110437
K2216364Certificate of AnalysisOct 17, 2022 C110437
K2216368Certificate of AnalysisOct 17, 2022 C110437
K2408128Certificate of AnalysisOct 17, 2022 C110437
L2410065Certificate of AnalysisOct 17, 2022 C110437
L2524090Certificate of AnalysisOct 17, 2022 C110437

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Chemical and Physical Properties
SolubilitySoluble in water (partly), 1 N HCl (25 mg/ml), ethanol, and acetic acid. Insoluble in acetone.
Sensitivitylight sensitive;Air sensitive;Moisture sensitive
Melt Point(°C)225°C
Molecular Weight121.160 g/mol
XLogP3-2.500
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass121.02 Da
Monoisotopic Mass121.02 Da
Topological Polar Surface Area64.300 Ų
Heavy Atom Count7
Formal Charge0
Complexity75.300
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Zhiping Qian, Rui Zhang, Haijun Hu, Yan Xiao, Hui Li, Xiaodong Sun, Tianyi Ma.  (2023)  Decoration of Defective Sites in Metal–Organic Frameworks to Construct Tight Heterojunction Photocatalyst for Hydrogen Production.  Solar RRL,  (22): (2300547).  [PMID:] [10.1002/solr.202300547]
2. Xuejing Wang, Yinyan Yuan, YiXiao Sun, Xue Liu, Mingze Ma, Renyin Zhang, Feng Shi.  (2022)  One-step facile preparation of carbon dots with high fluorescence quantum yield and application in rapid latent fingerprint detection.  RSC Advances,  12  (42): (27199-27205).  [PMID:36276032] [10.1039/D2RA05397G]
3. Ruihong Yao, Zhijian Li, Panpan Huo, Congcong Gong, Gang Liu, Chunhong Zheng, Shouzhi Pu.  (2022)  L-histidine functionalized ZiF-8 with aggregation-induced emission for detection of tetracycline.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:35759934] [10.1016/j.saa.2022.121546]
4. Shuting Chen, Weijia Wang, Shaohua Xu, Caili Fu, Shuyi Ji, Fang Luo, Cuiying Lin, Bin Qiu, Zhenyu Lin.  (2021)  Single nanoparticle identification coupled with auto-identify algorithm for rapid and accurate detection of L-histidine.  ANALYTICA CHIMICA ACTA,      [PMID:34753576] [10.1016/j.aca.2021.339162]
5. Chen Shuting, Chen Chaoqun, Wang Jian, Luo Fang, Guo Longhua, Qiu Bin, Lin Zhenyu.  (2021)  A Bright Nitrogen-doped-Carbon-Dots based Fluorescent Biosensor for Selective Detection of Copper Ions.  Journal of Analysis and Testing,  (1): (84-92).  [PMID:] [10.1007/s41664-021-00162-3]
6. Jian Zhang, Yanqing Miao, Zhao Cheng, Lingling Liang, Xiaoya Ma, Chunye Liu.  (2020)  A paper-based colorimetric assay system for sensitive cysteine detection using a fluorescent probe.  ANALYST,  145  (5): (1878-1884).  [PMID:31971166] [10.1039/C9AN02271F]
7. Cui Xu, Ruifang Guan, Duxia Cao, Kaerdun Liu, Qifeng Chen, Yunqiao Ding, Yun Yan.  (2019)  Bioinspired non-aromatic compounds emitters displaying aggregation independent emission and recoverable photo-bleaching.  TALANTA,      [PMID:31514871] [10.1016/j.talanta.2019.120232]
8. Guo-Cheng Han, Xiaorui Su, Jiating Hou, Annaleizle Ferranco, Xiao-Zhen Feng, Ruosheng Zeng, Zhencheng Chen, Heinz-Bernhard Kraatz.  (2018)  Disposable electrochemical sensors for hemoglobin detection based on ferrocenoyl cysteine conjugates modified electrode.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2018.11.042]
9. Qing Xiong, Jing Jin, Liqiong Lv, Zhisi Bu, Shengqiang Tong.  (2018)  Chiral ligand exchange countercurrent chromatography: Enantioseparation of amino acids.  JOURNAL OF SEPARATION SCIENCE,  41  (6): (1479-1488).  [PMID:29323783] [10.1002/jssc.201701117]
10. Jianping Li, Xionghui Ma, Mengxi Li, Yun Zhang.  (2017)  Does polysaccharide is an idea template selection for glycosyl imprinting?.  BIOSENSORS & BIOELECTRONICS,      [PMID:28818784] [10.1016/j.bios.2017.08.004]
11. Wang Shulong, Huang Wenfang, Lin Qingyan, Feng Yinyin, Wei Qingmin, Xu Jiayao, Wang Rong, Luo Zhihui.  (2024)  Design and synthesis of a novel chiral photoacoustic probe and accurate imaging detection of hydrogen peroxide in vivo.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,      [PMID:39078455] [10.1007/s00216-024-05463-x]
12. Zhen Zhang, Yue Wang, Shuai Lv, Hailin Cong, Youqing Shen, Bing Yu.  (2024)  Isocyanate-chitin modified microspheres for chiral drug separation in high performance liquid chromatography.  JOURNAL OF APPLIED POLYMER SCIENCE,  141  (27): (e55594).  [PMID:] [10.1002/app.55594]
13. Qinhua Liu, Xuan Kuang.  (2025)  Electrochemiluminescent Chiral Sensor Based on Covalent Organic Frameworks for Discrimination of Phenylalanine Enantiomers.  CHIRALITY,  37  (7): (e70040).  [PMID:40619728] [10.1002/chir.70040]
14. Liu Chunye, Miao Yanqing, Zhang Xuejiao, Zhang Shuli, Zhao Xiaojun.  (2020)  Colorimetric determination of cysteine by a paper-based assay system using aspartic acid modified gold nanoparticles.  MICROCHIMICA ACTA,  187  (6): (1-8).  [PMID:32476039] [10.1007/s00604-020-04333-4]
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