TNG908 - ≥98% , CAS No.2760481-53-4

CAS: 2760481-53-4 Cat. No.: T650705 Molecular Weight: 409.50

GRADE & PURITY ≥98%

Synonyms

N-(6-Amino-5-methylpyridin-3-yl)-2-((2R,5S)-2-(benzo[d]thiazol-5-yl)-5-methylpiperidin-1-yl)-2-oxoacetamide

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

TNG908 is an selective MTAP-co-PRMT5 inhibitor that crosses the blood-brain barrier and kills MTAP-deficient cancers.

Specifications

Synonyms

N-(6-Amino-5-methylpyridin-3-yl)-2-((2R, 5S)-2-(benzo[d]thiazol-5-yl)-5-methylpiperidin-1-yl)-2-oxoacetamide

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

TNG908 is a MTAP-cooperative PRMT5 inhibitor that can pass through the blood-brain barrier. TNG908 is 15 times more selective for MTAP cell lines than MTAP WT cell lines, and can be used in cancer research.

Storage

Protected from light, Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: CC1=CC(NC(C(N2[C@@H](C3=CC=C(SC=N4)C4=C3)CC[C@@H](C2)C)=O)=O)=CN=C1N
• Molecular Weight: 409.50

Chemical and Physical Properties

• Solubility: Soluble in DMSO（Sonification is recommended）
• Sensitivity: light sensitive