trans-Dehydroandrosterone（DHEA） - Moligand™, ≥99% , CAS No.53-43-0

Name: trans-Dehydroandrosterone（DHEA） - Moligand™, ≥99% , CAS No.53-43-0
Brand: Aladdin Scientific
SKU: D106380
Availability: InStock

CAS: 53-43-0 Cat. No.: D106380 Formula: C₁₉H₂₈O₂ Molecular Weight: 288.43 Beilstein Registry Number: 2058110 EC Number: 200-175-5

52 Citations COA

Skip to the end of the images gallery

trans-Dehydroandrosterone（DHEA） - Moligand™, ≥99% CAS No(53-43-0) D106380 by Aladdin Scientific

Skip to the beginning of the images gallery

AVAILABLE TO ORDER

GRADE & PURITY Moligand™ ? ≥99%

Synonyms

Storage

Room temperature

Shipped In

Normal

Specifications Product Properties Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates (CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties FAQs and Articles Citations of This Product Solution Calculators Reviews

🧪

Why this grade

Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 52 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms

Specifications & Purity

Moligand™, ≥99%

Biochemical and Physiological Mechanisms

Dehydroandrosterone (DHEA) is a negative modulator of GABAA receptors. It is a steroid secreted by the adrenal gland with both estrogenic and androgenic properties. DHEAs conversion to 5-androstenediol, a potent estrogen, enhances the growth and survival

Storage

Room temperature

Shipped In

Normal

Grade

Moligand™

Purity

≥99%

Product Properties

alogp

3.2

Names and Identifiers

Pubchem Sid

508812657

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508812657

Canonical Smiles

CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)O)C

IUPAC Name

(3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one

InChIKey

FMGSKLZLMKYGDP-USOAJAOKSA-N

INCHI

1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1

Isomeric SMILES

C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC=C4[C@@]3(CC[C@@H](C4)O)C

WGK Germany

RTECS

BV8396000

Molecular Weight

288.43

Beilstein

2058110

Reaxy-Rn

1915231

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1915231&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

<<<<<<< HEAD Download SDS → ======= Download SDS → >>>>>>> release248-p3

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Class Steroids and steroid derivatives
    - Subclass Androstane steroids

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Class	Steroids and steroid derivatives
Subclass	Androstane steroids
Intermediate Tree Nodes	Not available
Direct Parent	Androgens and derivatives
Alternative Parents	3-beta-hydroxysteroids 3-beta-hydroxy delta-5-steroids 17-oxosteroids Delta-5-steroids Secondary alcohols Ketones Cyclic alcohols and derivatives Organic oxides Hydrocarbon derivatives
Molecular Framework	Aliphatic homopolycyclic compounds
Substituents	Androgen-skeleton - 3-hydroxy-delta-5-steroid - 3-hydroxysteroid - 3-beta-hydroxysteroid - 3-beta-hydroxy-delta-5-steroid - Oxosteroid - 17-oxosteroid - Hydroxysteroid - Delta-5-steroid - Cyclic alcohol - Secondary alcohol - Ketone - Organic oxygen compound - Carbonyl group - Hydrocarbon derivative - Alcohol - Organooxygen compound - Organic oxide - Aliphatic homopolycyclic compound
Description	This compound belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans.
External Descriptors	C19 steroids (androgens) and derivatives
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

SHBG Tchem Sex hormone-binding globulin (1 Activities)

Discover Target: SHBG

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOA Tclin Monoamine oxidase A (11911 Activities)

Discover Target: MAOA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NPC1L1 Tclin Niemann-Pick C1-like protein 1 (346 Activities)

Discover Target: NPC1L1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SULT2A1 Tbio Alcohol sulfotransferase (89 Activities)

Discover Target: SULT2A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SERPINA6 Tchem Corticosteroid binding globulin (274 Activities)

Discover Target: SERPINA6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 Activities)

Discover Target: UGT1A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A-375 (9258 Activities)

Lot Number	Certificate Type	Date	Item
F2615338	Certificate of Analysis	May 30, 2026	D106380
F2615337	Certificate of Analysis	May 30, 2026	D106380
F2615336	Certificate of Analysis	May 30, 2026	D106380
F2615335	Certificate of Analysis	May 30, 2026	D106380
F2615332	Certificate of Analysis	May 30, 2026	D106380
L2503300	Certificate of Analysis	Nov 12, 2025	D106380
L2503299	Certificate of Analysis	Nov 12, 2025	D106380
L2503298	Certificate of Analysis	Nov 12, 2025	D106380
L2503297	Certificate of Analysis	Nov 12, 2025	D106380
L2503296	Certificate of Analysis	Nov 12, 2025	D106380
G2518234	Certificate of Analysis	May 10, 2025	D106380
G2518233	Certificate of Analysis	May 10, 2025	D106380
A2612043	Certificate of Analysis	May 10, 2025	D106380
G2518232	Certificate of Analysis	May 10, 2025	D106380
K2511087	Certificate of Analysis	May 10, 2025	D106380
E2514030	Certificate of Analysis	Nov 09, 2024	D106380
L2410028	Certificate of Analysis	Nov 09, 2024	D106380
K2426432	Certificate of Analysis	Nov 09, 2024	D106380
K2426433	Certificate of Analysis	Nov 09, 2024	D106380
K2426458	Certificate of Analysis	Nov 09, 2024	D106380
J2431150	Certificate of Analysis	Jun 06, 2024	D106380
F2421219	Certificate of Analysis	Jun 06, 2024	D106380
F2421218	Certificate of Analysis	Jun 06, 2024	D106380
F2421217	Certificate of Analysis	Jun 06, 2024	D106380
F2421216	Certificate of Analysis	Jun 06, 2024	D106380
F2421215	Certificate of Analysis	Jun 06, 2024	D106380
J2431677	Certificate of Analysis	Mar 21, 2024	D106380
J2431675	Certificate of Analysis	Mar 21, 2024	D106380
J2431676	Certificate of Analysis	Mar 21, 2024	D106380
E2324271	Certificate of Analysis	Sep 16, 2023	D106380
A2403044	Certificate of Analysis	Jul 31, 2023	D106380
H2316367	Certificate of Analysis	Jul 31, 2023	D106380
H2316371	Certificate of Analysis	Jul 31, 2023	D106380
H2316370	Certificate of Analysis	Jul 31, 2023	D106380
H2316369	Certificate of Analysis	Jul 31, 2023	D106380
H2316368	Certificate of Analysis	Jul 31, 2023	D106380
F2315991	Certificate of Analysis	Jun 29, 2023	D106380
A2220037	Certificate of Analysis	Feb 17, 2022	D106380
E2207029	Certificate of Analysis	Feb 14, 2022	D106380
E2207018	Certificate of Analysis	Feb 14, 2022	D106380
E2207019	Certificate of Analysis	Feb 14, 2022	D106380
E2207023	Certificate of Analysis	Feb 14, 2022	D106380
E2207024	Certificate of Analysis	Feb 14, 2022	D106380
L2216807	Certificate of Analysis	Feb 14, 2022	D106380
F2315996	Certificate of Analysis	Feb 14, 2022	D106380
F2315993	Certificate of Analysis	Feb 14, 2022	D106380
A2221040	Certificate of Analysis	Jan 27, 2022	D106380
E1618016	Certificate of Analysis	Jan 24, 2022	D106380
C1829062	Certificate of Analysis	Jan 24, 2022	D106380

x_melt_point_char	146-151°C
Molecular Weight	288.400 g/mol
XLogP3	3.200
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	288.209 Da
Monoisotopic Mass	288.209 Da
Topological Polar Surface Area	37.300 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	508.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	6
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

trans-Dehydroandrosterone（DHEA） - Moligand™, ≥99% , CAS No.53-43-0

Storage & shipping

Quality documents

Literature proof

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Customer Reviews

📚 Citations by Application

Need help choosing the grade?

View related series

Related Products