2,5-Dimethylfuran - ≥99% , CAS No.625-86-5

CAS: 625-86-5 Cat. No.: D113405 Molecular Weight: 96.13 Beilstein Registry Number: 106449 EC Number: 210-914-3
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Synonyms
EINECS 210-914-3 | 2,5-DIMETYLFURAN | DR5HL9OJ7Y | 2,5-DIMETHYLFURAN [FHFI] | 2,5-Dimethylfuran, 99% | DTXSID7022093 | DTXCID102093 | Furan, 2,5-dimethyl- | 2,5-Dimethylfuran 1000 microg/mL in Acetonitrile | 2,5-Dimethylfuran, >=99% | FT-0655041 | 2,5-DIM
Storage
Room temperature,Argon charged
Shipped In
FedEx DG Service
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5ml
D113405-5ml
6
$9.90
25ml
D113405-25ml
6

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$35.90
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100ml
D113405-100ml
10

$59.90

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Save $41.00 (40.63%)
500ml
D113405-500ml
1

$261.90

$453.90
Save $192.00 (42.30%)
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature,Argon charged Ships FedEx DG Service Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 48 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

2,5-Dimethylfuran is a heterocyclic furan used as a building block in organic synthesis.

Product Application:

2,5-Dimethylfuran (DMF) can be used for:
1、Preparation of external maleimide dimethylfuran ring adducts as reactants for the synthesis of oligonucleotide conjugates.
2、As an arynophile, 1,4-dimethyl-1,4-dihydro-1,4-epoxynaphthalene (heavy benzene) was synthesized by reacting with a mixture of neopentyl glycol and 2-hydroxyphenylboronic acid under strong alkaline conditions.
3、As a precursor, p-xylene was prepared through Diels Alder cycloaddition and subsequent dehydration reactions.

Specifications

Synonyms
EINECS 210-914-3 | 2, 5-DIMETYLFURAN | DR5HL9OJ7Y | 2, 5-DIMETHYLFURAN [FHFI] | 2, 5-Dimethylfuran, 99% | DTXSID7022093 | DTXCID102093 | Furan, 2, 5-dimethyl- | 2, 5-Dimethylfuran 1000 microg/mL in Acetonitrile | 2, 5-Dimethylfuran, >=99% | FT-0655041 | 2, 5-DIM
Specifications & Purity
≥99%
Storage
Room temperature, Argon charged
Shipped In
FedEx DG Service
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥99%
Names and Identifiers
Pubchem Sid488181597
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488181597
Canonical SmilesCC1=CC=C(O1)C
IUPAC Name2,5-dimethylfuran
InChIKeyGSNUFIFRDBKVIE-UHFFFAOYSA-N
INCHI1S/C6H8O/c1-5-3-4-6(2)7-5/h3-4H,1-2H3
Isomeric SMILES CC1=CC=C(O1)C
WGK Germany 3
RTECS LU0875000
UN Number 1993
Packing Group I
Molecular Weight 96.13
Beilstein 106449
Reaxy-Rn 106449
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=106449&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassHeteroaromatic compounds
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentHeteroaromatic compounds
Alternative Parents Furans  Oxacyclic compounds  Organooxygen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Heteroaromatic compound - Furan - Oxacycle - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as heteroaromatic compounds. These are compounds containing an aromatic ring where a carbon atom is linked to an hetero atom.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CXCL8 Tchem Interleukin-8 (642 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

29 results found

Lot NumberCertificate TypeDateItem
L2524345Certificate of AnalysisDec 15, 2025 D113405
L2524344Certificate of AnalysisDec 15, 2025 D113405
L2524336Certificate of AnalysisDec 15, 2025 D113405
L2524331Certificate of AnalysisDec 15, 2025 D113405
C2518779Certificate of AnalysisMar 05, 2025 D113405
H2512079Certificate of AnalysisMar 05, 2025 D113405
C2518780Certificate of AnalysisMar 05, 2025 D113405
C2518778Certificate of AnalysisMar 05, 2025 D113405
C2518777Certificate of AnalysisMar 05, 2025 D113405
D2416198Certificate of AnalysisMar 15, 2024 D113405
D2416211Certificate of AnalysisMar 15, 2024 D113405
J2412057Certificate of AnalysisMar 15, 2024 D113405
C2405414Certificate of AnalysisFeb 26, 2024 D113405
L2322256Certificate of AnalysisDec 12, 2023 D113405
L2322255Certificate of AnalysisDec 12, 2023 D113405
L2322254Certificate of AnalysisDec 12, 2023 D113405
L2322257Certificate of AnalysisDec 12, 2023 D113405
J2412052Certificate of AnalysisDec 12, 2023 D113405
C2302351Certificate of AnalysisDec 08, 2022 D113405
C2302385Certificate of AnalysisDec 08, 2022 D113405
C2302384Certificate of AnalysisDec 08, 2022 D113405
C2302383Certificate of AnalysisDec 08, 2022 D113405
C2302348Certificate of AnalysisDec 08, 2022 D113405
I2321056Certificate of AnalysisJul 27, 2022 D113405
H2224184Certificate of AnalysisJul 27, 2022 D113405
H2224182Certificate of AnalysisJul 27, 2022 D113405
H2224181Certificate of AnalysisJul 27, 2022 D113405
H2224177Certificate of AnalysisJul 27, 2022 D113405
C23311535Certificate of AnalysisJul 27, 2022 D113405

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Chemical and Physical Properties
SolubilitySlightly miscible with water. Miscible with ethanol and fats.
SensitivityHeat sensitive
Refractive Index1.44-1.442
Flash Point(°F)33.8°F
Flash Point(°C)1°C
Boil Point(°C)92-94°C
Melt Point(°C)-62°C
Molecular Weight96.130 g/mol
XLogP32.200
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass96.0575 Da
Monoisotopic Mass96.0575 Da
Topological Polar Surface Area13.100 Ų
Heavy Atom Count7
Formal Charge0
Complexity53.200
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Chengming Wu, Hongbo Chen, Jifan Li, Chun-Ling Liu, Wen-Sheng Dong.  (2023)  Zirconium-tin phosphate as an efficient catalyst for renewable p-xylene synthesis from biobased 2,5-dimethylfuran and ethylene.  APPLIED CATALYSIS A-GENERAL,      [PMID:] [10.1016/j.apcata.2023.119521]
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17. Jing Fan, Peng Liu, Zhiqiang Gao, Fenhong Song.  (2021)  Research on the liquid thermal conductivity of three alternative fuels: Tetrahydrofuran, 2-methylfuran and 2,5- dimethylfuran.  FLUID PHASE EQUILIBRIA,      [PMID:] [10.1016/j.fluid.2021.113288]
18. Yingchang Zou, Yu Wang, Zaile Jiang, Yuan Zhou, Ying Chen, Yanjie Hu, Guobao Jiang, Duan Xie.  (2021)  Breath profile as composite biomarkers for lung cancer diagnosis.  LUNG CANCER,      [PMID:33563485] [10.1016/j.lungcan.2021.01.020]
19. Yuchen Ya, Xiaokang Nie, Weiwei Han, Longkai Xiang, Mingyan Gu, Huaqiang Chu.  (2020)  Effects of 2, 5–dimethylfuran/ethanol addition on soot formation in n-heptane/iso-octane/air coflow diffusion flames.  ENERGY,      [PMID:] [10.1016/j.energy.2020.118661]
20. Ting Wang, Junnan Wei, Yunchao Feng, Huai Liu, Xing Tang, Xianhai Zeng, Yong Sun, Tingzhou Lei, Lu Lin.  (2020)  Efficient synthesis of bio-based monomer 2,5-bishydroxymethylfuran by the solvent-free hydrogenation of 5-hydroxymethylfurfural-based deep eutectic mixture.  JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY,  95  (6): (1748-1755).  [PMID:] [10.1002/jctb.6373]
21. Lele Jin, Wenzhi Li, Qiying Liu, Longlong Ma, Chao Hu, Ajibola T. Ogunbiyi, Mingwei Wu, Qi Zhang.  (2019)  High performance of Mo-promoted Ir/SiO2 catalysts combined with HZSM-5 toward the conversion of cellulose to C5/C6 alkanes.  BIORESOURCE TECHNOLOGY,      [PMID:31796376] [10.1016/j.biortech.2019.122492]
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23. Lele Jin, Wenzhi Li, Qiying Liu, Longlong Ma, Song Li, Yang Liu, Baikai Zhang, Qi Zhang.  (2019)  Catalytic conversion of cellulose to C5/C6 alkanes over Ir-VOx/SO2 combined with HZSM-5 in n-dodecane/water system.  FUEL PROCESSING TECHNOLOGY,      [PMID:] [10.1016/j.fuproc.2019.106161]
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42. Bo Yang, Jiawei Xie, Yuxuan Liang, Xiumei Ma, Huyao Ge, Xueping Wang, Zhaohui Wang, Qiuyu Zhang, Ji-Jun Zou, Junjian Xie.  (2025)  Self-photosensitized cycloaddition induced synthesis of a high-density fuel with ultra-low freezing point using bulk bio-benzaldehyde and furans.  GREEN CHEMISTRY,      [PMID:] [10.1039/D4GC06345G]
43. Yi Yang, Yuxi Si, Libin Liu, Hairui Lin, Chuan Qin, Dangguo Cheng, Youwei Cheng.  (2025)  Selective Hydrogenation of 5-Hydroxymethylfurfural to 2,5-Bis(hydroxymethyl)furan over Hydroxyl-Enriched Pt/CeO2 Catalysts.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.5c00644]
44. Jiahui Chen, Xian Pan, Xinchi Zhang, Xin Zhou, Shiliang Wu, Youn-Sang Bae, Ismagil Shakirovich Khusnutdinov, Feng Gong, Tao Li, Huiyan Zhang, Rui Xiao.  (2025)  Electrochemical dimerization of furfural and 5-hydroxymethylfurfural into aviation fuel precursors: Optimization and mechanistic insights.  Journal of Cleaner Production,      [PMID:] [10.1016/j.jclepro.2025.146968]
45. Kaili He, Mouming Zhao, Xing Tong, Yunzi Feng.  (2025)  Reveal the flavor quality changes of soy sauce during shelf life through metabolomics.  FOOD CHEMISTRY,      [PMID:41443118] [10.1016/j.foodchem.2025.147650]
46. Shangpu Zhuang, Yilin Lei, Fan Xue, Tao Wei, Di Hao, Luming Qi, Lichun Nian, Yuyu Sun, Mifen Cui, Zhuxiu Zhang, Ruiping Wei, Jihai Tang, Xu Qiao.  (2025)  Cu/CexZr10-x Derived from Zr-Incorporated Ce-MOF with Tunable Oxygen Vacancies and Acid Sites for Efficient Selective Hydrodeoxygenation of 5-HMF to 2,5-DMF.  LANGMUIR,      [PMID:41460984] [10.1021/acs.langmuir.5c05359]
47. Zhiyang Tang, Xianyuan Wu, Jie Qu, Xinjun He, Fukun Li, Jinxing Long, Qiang Zeng, Haixia Su, Hongyan He, Xuehui Li.  (2026)  Syngas-Promoted Selective Catalytic Hydrogenolysis of Cellulose into C6-Ketones.  Green Energy & Environment,      [PMID:] [10.1016/j.gee.2026.02.003]
48. Haojie Feng, Ju Huang, Yuanyuan Wang, Shichao Du, Xiaolei Wang, Ying Xie, Yu Fu, Mingxia Li, Zhimin Chen, Zhiyu Ren.  (2026)  Expanding the operational horizon of ampere-scale biomass electrorefining via decoupling competing pathways on cuprous-integrated spinel heterostructures.  APPLIED CATALYSIS B-ENVIRONMENTAL,      [PMID:] [10.1016/j.apcatb.2026.126945]
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